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Precautions

Do NOT use Topamax if:

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• you're allergic to the ingredient in Topamax

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• you take a carbonic anhydrase inhibitor (eg, acetazolamide).

Contact your physician or doctor immediately if some of these connect with you.

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Some medical ailments may interact with Topamax. Tell your health care provider if you have any medical ailments, particularly if any in the following connect with you:

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• if you might be pregnant, about to get pregnant, or are breast-feeding

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• if you consider any prescription or nonprescription medicine, herbal preparation, or dietary supplement

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• for those who have allergies to medicines, foods, and other substances

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• in case you have liver or kidney problems, kidney stones, osteoporosis (weak bones), or metabolic problems, you are drinking alcoholic beverages regularly, or you are on a ketogenic diet

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• when you have diarrhea, lung or breathing problems, or low bicarbonate levels in the blood, or perhaps you is going to be having surgery

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• for those who have a history of status epilepticus (continuous seizure activity or even a compilation of seizures with out a full come back to consciousness)

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Some medicines may talk with Topamax. Tell your health care provider if you are taking another medicines, especially any with the following:

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• Anticholinergics (eg, benztropine), carbonic anhydrase inhibitors (eg, acetazolamide), haloperidol, or tricyclic antidepressants (eg, nortriptyline) as the probability of decreased sweating could be increased

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• Valproic acid just because a serious unwanted effect with the signs of confusion, lethargy, and vomiting may occur

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• Metformin or pioglitazone because blood glucose control could possibly be altered; monitor your blood sugar carefully if you utilize Topamax with metformin or pioglitazone

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• Hydrochlorothiazide since it might increase the chance of Topamax's unwanted effects

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• Carbamazepine or hydantoins (eg, phenytoin) since they may decrease Topamax's effectiveness
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• Lithium because Topamax could have an effect on lithium blood levels
• Hormonal contraception (eg, contraception pills) or risperidone his or her effectiveness could be decreased by Topamax.

This might not be a complete set of all interactions which could occur. Ask your health care provider if Topamax may interact with medicines which you take. Check with your medical provider before you start, stop, or affect the dose associated with a medicine.

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Important safety information:

• Topamax could potentially cause drowsiness, dizziness, confusion, or trouble concentrating. These effects could possibly be worse if you get it with alcohol or certain medicines. Use Topamax with caution. Do not drive or perform other possible unsafe tasks and soon you discover how you reply to it.

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• Do not consume alcohol or use medicines that could cause drowsiness (eg, sleep aids, muscle relaxers) while you're using Topamax; it may help to increase their effects. Ask your pharmacist in case you have questions on which medicines could potentially cause drowsiness.

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• Topamax may reduce sweating, that may raise body's temperature, especially in children. This risk is greater in hot weather and/or during vigorous exercise. Drink lots of fluids. Dress lightly while in hot climates or during exercise. Check carefully for signs of decreased sweating. If this occurs, promptly seek cooler or air-conditioned shelter and/or stop exercising. Seek medical help without delay when you have unexplained fever, or when you have mental or mood changes, headache, or dizziness.

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• Tell a medical expert or dentist that you simply take Topamax before you have any medical or dental treatments, emergency care, or surgery.

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• Hormonal birth control method (eg, contraception pills) may well not be well while you're using Topamax. To prevent pregnancy, work with an extra kind of birth control method (eg, condoms).

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• Lab tests, including serum bicarbonate levels, could possibly be performed whilst you use Topamax. These tests could be accustomed to monitor your problem or pay attention to unwanted effects. Be sure to keep all doctor and lab appointments.

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• Use Topamax with caution inside elderly; they may be more understanding of its effects.

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• Caution is advised when working with Topamax in children; they may be more sensitive to its effects, especially decreased sweating and decreased bicarbonate levels.

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• Topamax should be used with extreme caution in youngsters for migraines and in kids  younger than 2 years old for seizures; safety and effectiveness during these children haven't been confirmed.

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• Pregnancy and breast-feeding: If you become pregnant, contact your medical professional. You will need to discuss the benefits and perils associated with using Topamax while you might be pregnant. Topamax is situated in breast milk. If you might be or will be breast-feeding when you use Topamax, check with your physician. Discuss any possible risks in your baby.

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