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INDICATIONSLevodopa is changed to a chemical called dopamine (DOE pa meen) inside brain. Symptoms of Parkinson's disease could be brought on by lower levels of dopamine inside the brain.

Carbidopa helps prevent the breakdown of levodopa before it could achieve the brain and take effect.

The mix of carbidopa and levodopa is used to take care of Parkinson symptoms like muscle stiffness, tremors, spasms, and poor muscle control. This medication is additionally used to take care of Parkinson symptoms caused by deadly carbon monoxide poisoning or manganese intoxication.

Carbidopa and levodopa may also be used for other purposes not listed on this medication guide.


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If you happen to be already taking levodopa (Larodopa, Dopar), you need to stop taking it no less than 12 hours before you start taking carbidopa and levodopa.

Take exactly as prescribed from your doctor. Do not take in larger or smaller amounts and for over recommended. Follow the directions on your own prescription label.

Carbidopa and levodopa could be taken with or without food. Take your doses at regular intervals to maintain a steady quantity of the drug within you all the time.
Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. Breaking or opening the pill could cause too much of the drug to be sold at one time.

The regular tablet may be broken or crushed as required to make it easier to swallow.

To go ahead and take orally disintegrating tablet (Parcopa):

Keep these days in their blister pack until you're ready to go ahead and take medicine. Open the package and peel back the foil from named blister. Do not push a tablet from the foil or you may damage named.

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Using dry hands, remove today and put it in your mouth. It will start to dissolve without delay.

Do not swallow named whole. Allow it to dissolve in your mouth without chewing. Swallow several times as the tablet dissolves.
It may take around weeks utilizing carbidopa and levodopa before your symptoms improve. For best results, keep using the medication as directed. Talk with a medical expert in case your symptoms tend not to improve soon after weeks of treatment. Also tell your doctor if the connection between this medication manage to wear off quickly in between doses.

To make sure this prescription medication is helping your trouble and is not causing harmful effects, your blood must be tested often. Your heart, liver, and kidney function can also need to be tested. Visit your medical professional regularly.

This medication can cause unusual results with certain tests. Tell any doctor who treats you that you are using carbidopa and levodopa.

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Store at room temperature away from moisture, heat, and lightweight.


Active Ingredient: Carbidopa and Levodopa

Side Effects

You may notice that your sweat, urine, or saliva appears dark in color, like red, brown, or black. This is not a harmful side effect, nevertheless it might cause staining of the clothes or bed sheets.
Get emergency medical help for those who have some of these warning signs of a hypersensitive reaction: hives; lack of breath; swelling of your respective face, lips, tongue, or throat. Call your doctor simultaneously in case you have some of these serious unwanted side effects:

restless muscle movements in your eyes, tongue, jaw, or neck;

worsening of tremors (uncontrolled shaking);

high fever, stiff muscles, sweating, fast or uneven heartbeats, rapid breathing, feeling like you might pass out;

seizure (convulsions);

painful or difficult urination;

severe nausea, vomiting, or diarrhea;

uneven heart rate or fluttering within your chest;

confusion, hallucinations, anxiety, agitation, depressed mood, thoughts of suicide or hurting yourself;

chest pain or heavy feeling, pain spreading on the arm or shoulder.

Less serious side effects might include:

mild nausea, dry mouth, lack of appetite, heartburn, diarrhea, constipation;

headache, dizziness, drowsiness, blurred vision;

sneezing, stuffy nose, cough, and other cold symptoms;

sleep problems (insomnia), strange dreams;

muscle pain, numbness or tingly feeling; or

skin rash or itching.

This is not a complete set of unwanted side effects while others may occur. Call your medical professional for health advice about side effects.

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Do not take carbidopa and levodopa for those who have used an MAO inhibitor like isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) within the past fourteen days. Serious, life-threatening unwanted effects can happen invest the carbidopa and levodopa before the MAO inhibitor has cleared from your body. 

You must not take medicines if you happen to be allergic to carbidopa (Lodosyn) or levodopa (Larodopa), or in case you have:

narrow-angle glaucoma;

unusual wounds which may have not been checked with a doctor; or

a good malignant melanoma (cancer of the skin).

If you've all of these other difficulties, you need a dose adjustment or special tests:

heart disease, blood pressure, coronary artery disease, a heart rhythm disorder, or a prior heart attack;

asthma, chronic obstructive pulmonary disease (COPD), or other breathing disorder;
liver or kidney disease;

an endocrine (hormonal) disease;

a stomach or intestinal ulcer;

wide-angle glaucoma; or

depression and other mental illness.
Carbidopa and levodopa may cause you to get to sleep during normal daytime activities like working, talking, eating, or driving. You may fall asleep suddenly, even after feeling alert. Tell your doctor when you have any difficulty with daytime sleepiness or drowsiness.

You could have increased sexual urges, unusual urges to gamble, or any other intense urges while taking carbidopa and levodopa. It is not known whether the medicine actually causes this effect. Talk with your medical professional if you think maybe you have any intense or unusual urges while taking carbidopa and levodopa.

Some people taking medicines for Parkinson's disease are suffering from cancer of the skin (melanoma). However, people with Parkinson's disease may have a greater risk than most of the people for developing melanoma. Talk to your medical professional about your specific risk and what skin symptoms to look at for. You may need to have regular skin exams.
FDA pregnancy category C. It is not known whether carbidopa and levodopa will harm an baby. Tell your physician if you're pregnant or want to get pregnant with all the medicines. Carbidopa and levodopa may pass into breast milk and can harm a nursing baby. Do not use this medication without telling your doctor if you're breast-feeding your baby.

The disintegrating tablet (such as Parcopa) may contain phenylalanine. Talk to your medical professional before by using this way of carbidopa and levodopa in case you have phenylketonuria (PKU).

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If you missed the dose take it whenever you remember. Skip the missed dose whether it is almost time for your forthcoming scheduled dose. Do not take extra medicine to create inside the missed dose.


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