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Promethazine is a group of drugs called phenothiazines (FEEN-oh-THYE-a-zeens). It works by changing those things of chemicals with your brain. Promethazine also acts being an antihistamine. It blocks the consequences from the naturally sourced chemical histamine with your body.

Promethazine can be used to treat hypersensitivity including itching, runny nose, sneezing, itchy or watery eyes, hives, and itchy skin rashes.

Promethazine also prevents motion sickness, and treats nausea and vomiting or pain after surgery. It is also used like a sedative or sleep aid.

Promethazine isn't to be used in treating the signs of asthma, pneumonia, and other lower respiratory tract infections.


Take promethazine the same manner prescribed from your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on the prescription label.

Your doctor may occasionally alter your dose to successfully obtain the best is a result of prescription drugs.

Promethazine might be taken with or without food or milk.

Measure liquid medicine having a marked measuring spoon or medicine cup, not which has a regular table spoon. If you don't use a dose-measuring device, ask the pharmacist first.

Call your medical professional if the symptoms tend not to improve, or if they worsen while taking promethazine.

This medication may cause you to definitely have unusual results with certain medical tests. Tell any doctor who treats you that you will be using promethazine.

Seek emergency medical attention if you believe you might have used which is not this medicine. Overdose symptoms can include severe drowsiness, dizziness, dry mouth, large pupils, flushing, nausea, vomiting, shallow breathing, and fainting.


Take it as prescribed from your doctor.


Store promethazine at room temperature far from moisture, heat, and light-weight.


Active Ingredient: Promethazine



Side Effects

Get emergency medical help if you have any of these warning signs of a hypersensitivity: hives; breathlessness; swelling of your respective face, lips, tongue, or throat. Stop using promethazine and call a medical expert at once if you might have some of these serious side effects:

twitching, or uncontrollable movements of your respective eyes, lips, tongue, face, arms, or legs;

tremor (uncontrolled shaking), drooling, trouble swallowing, issues with balance or walking;

feeling restless, jittery, or agitated;

high fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, rapid breathing;

feeling as if you might faint;

seizure (convulsions);

pale skin, easy bruising or bleeding, fever, sore throat, flu symptoms;

decreased night vision, tunnel vision, watery eyes, increased sensitivity to light;

hallucinations, agitation;

nausea and stomach pain, skin rash, and jaundice (yellowing with the skin or eyes);

urinating lower than usual you aren't in any way;

joint pain or swelling with fever, swollen glands, muscle aches, chest pain, vomiting, unusual thoughts or behavior, and patchy complexion; or

slow heartrate, weak pulse, fainting, slow breathing (breathing may stop).

Less serious promethazine unwanted effects may include:

dizziness, drowsiness, anxiety;

blurred vision, dry mouth, stuffy nose;

ringing within your ears;

weight gain, swelling inside your hands or feet;

impotence, trouble owning an orgasm; or


This isn't a complete set of negative effects while others may occur. Tell your medical professional about any unusual or bothersome side effect.


Stop using promethazine and call your medical professional immediately if you have twitching or uncontrollable movements of one's eyes, lips, tongue, face, arms, or legs. These could be early signs of dangerous unwanted side effects. Promethazine can cause unwanted effects that may impair your thinking or reactions. Be careful should you drive or do just about anything that requires one to be awake and alert. Avoid having a drink, which can increase some in the side effects of promethazine. There are many other medicines that could interact with promethazine. Tell a medical expert about all the prescription and over-the-counter medications you utilize. This includes vitamins, minerals, herbal products, and prescription drugs given by other doctors. Do not use a new medication without telling your doctor. Keep a list together with you of each of the medicines you employ and show this list to any doctor and other healthcare provider who treats you.

Important safety information:

Promethazine should not be presented to a child younger than a couple of years old. Promethazine may cause severe breathing problems or death in a child younger than 2. Carefully follow your medical professional's instructions when giving this medicine to a kid of any age. Do not use prescription drugs if you have severe asthma, emphysema, or any other breathing problem, or in the event you are allergic to promethazine or other phenothiazines for example chlorpromazine (Thorazine), fluphenazine (Permitil), perphenazine (Trilafon), prochlorperazine (Compazine, Compro), thioridazine (Mellaril), or trifluoperazine (Stelazine).

If you've certain conditions, you need a dose adjustment or special tests to soundly use this medication. Before you take promethazine, tell your medical professional if you have:

a good seizures;

heart disease or hypertension;

liver or kidney disease;

severe asthma, emphysema, chronic obstructive pulmonary disease (COPD) or any other breathing problem;

sleep apnea (breathing stops while sleeping);


a stomach ulcer or digestive obstruction;

bone marrow depression;

adrenal gland tumor (pheochromocytoma);

enlarged prostate or issues with urination;

low amounts of calcium with your blood (hypocalcemia); or

if you might have ever were built with a serious side-effect when using promethazine or some other phenothiazine.

FDA pregnancy category C. It is not known whether promethazine is harmful for an baby. Tell your physician in the event you are pregnant or intend to get pregnant during treatment. It is just not known whether promethazine passes into breast milk or if it may harm a nursing baby. Do not use this medication without telling your medical professional in case you are breast-feeding your baby. Older adults could possibly be prone to have unwanted effects from promethazine.

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