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Micronase (Glyburide) is surely an oral diabetes medicine that helps control blood sugar.

Glyburide is employed to treat diabetes type 2 symptoms.

This medicine is not for treating type 1 diabetes.

Glyburide could also be used for other purposes unlisted within this medication guide.


Take exactly as prescribed because of your doctor. Do not take in larger or smaller amounts and longer than recommended. Follow the directions on your prescription label. Your doctor may occasionally make positive changes to dose to make sure you get the best results.

Take glyburide together with your first meal during the day, unless your physician tells you otherwise.

Your blood glucose will need to be checked often, and you might need other blood tests at your physician's office. Visit a medical expert regularly.
Know the signs and symptoms of low blood sugar (hypoglycemia) and ways to recognize them: headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating.

Always keep a method to obtain sugar accessible in case you might have signs and symptoms of low blood sugar. Sugar sources include orange juice, glucose gel, candy, or milk. If you might have severe hypoglycemia and should not eat or drink, readily injection of glucagon. Your doctor can provide you with a prescription for a glucagon emergency injection kit and inform you the way to supply the injection.

Also await signs of blood glucose levels that is certainly too high (hyperglycemia). These symptoms include increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, and weight reduction.

Check your blood sugar levels carefully within a time of stress or illness, in case you travel, exercise more than usual, consume alcohol, or skip meals. These things could affect your blood sugar levels plus your dose needs could also change.

Your doctor might prefer one to stop taking glyburide for a short period of time in the event you get ill, have a fever or infection, or if you've surgical treatment or a medical emergency.
Ask your doctor how to adjust your glyburide dose if required. Do not improve your medication dose or schedule without a medical expert's advice.

If you will find any adjustments to the manufacturer, strength, or form of glyburide you use, your dosage needs may change. Always check your refills to ensure that you have received the proper logo and sort of medicine prescribed by your doctor.


Take as prescribed from your doctor.


Store at room temperature, protected against moisture, heat, and light.


Active ingredient: Glyburide

Side Effects

Stop using glyburide and have emergency medical help if you have these indications of a hypersensitive reaction: hives; lack of breath; swelling of the face, lips, tongue, or throat. Stop taking prescription drugs and call your physician at the same time if you might have all of these serious side effects:

nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of your skin or eyes);

pale skin, confusion or weakness;

easy bruising or bleeding, purple or red pinpoint spots under your skin; or

headache, trouble concentrating, memory problems, feeling unsteady, hallucinations, fainting, seizure, shallow breathing or breathing that stops.

Less serious side effects may include:

mild nausea, heartburn, feeling full;

joint or muscle pain;

blurred vision; or

mild itching or skin rash.

This is not a complete listing of unwanted side effects while others may occur. Call a medical expert for health advice about unwanted effects.


You must avoid using medicines in case you are allergic to glyburide, or:

in case you are receiving care with bosentan (Tracleer);

if you might have type 1 diabetes; or

if you are in a state of diabetic ketoacidosis (call a medical expert for treatment with insulin).

To be sure you can safely take glyburide, tell your physician if you've these other conditions:

hemolytic anemia (deficiencies in red blood cells);

an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD);

a nerve disorder affecting bodily functions;

liver or kidney disease;

in the event you are allergic to sulfa drugs; or

if you have been using insulin or taking chlorpropamide (Diabinese).

Certain oral diabetes medications may raise your risk of serious cardiovascular disease. However, not taking care of your diabetes damages your heart and also other organs. Talk to a medical expert regarding the risks and benefits of handling your diabetes with glyburide.

FDA pregnancy category C. It is not known whether glyburide will harm an child. Similar diabetes medications have caused severe hypoglycemia in infants whose mothers had used the medication near the duration of delivery. Tell your physician in case you are pregnant or plan to get pregnant with all the this medication. It is not known whether glyburide passes into breast milk or if it could possibly harm a nursing baby.

Do not use medicines without telling your medical professional in the event you are breast-feeding an infant. Older adults could possibly be more prone to have low blood glucose while taking glyburide.


Important safety information:

You should avoid using this medication in the event you are allergic to glyburide, in the event you are undergoing treatment with bosentan (Tracleer), if you've type 1 diabetes, or in case you are in a state of diabetic ketoacidosis (call your medical professional for treatment with insulin).

Before taking glyburide, tell a medical expert in the event you are allergic to sulfa drugs, if you might have been using insulin or chlorpropamide (Diabinese), or if you have hemolytic anemia (deficiencies in red blood cells), an enzyme deficiency (G6PD), a nerve disorder, liver disease, or kidney disease.

Take care not to let your blood glucose get too low. Low blood sugar levels (hypoglycemia) can occur if you skip lunch, exercise to much time, drink alcohol, or are under stress. Symptoms include headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating. Carry hard candy or glucose tablets along with you in case you have low blood glucose. Other sugar sources include orange juice and milk. Be sure your household and good friends know how to assist you in an urgent situation.

Drug interactions

Tell your physician about all the medications you have, especially:

a blood thinner for example warfarin (Coumadin, Jantoven);

cyclosporine (Gengraf, Neoral, Sandimmune);

disopyramide (Norpace);

fluconazole (Diflucan), ketoconazole (Nizoral);

fluoxetine (Prozac);

rifampin (Rifadin, Rimactane, Rifater);

an ACE inhibitor such as enalapril (Vasotec), lisinopril (Prinivil, Zestril), ramipril (Altace), and others; or

an antibiotic such as ciprofloxacin (Cipro), levofloxacin (Levaquin), while others.

Using certain medicines can make it tougher for one to tell when you've low blood glucose. Tell your doctor in the event you use these things:

albuterol (Proventil, Ventolin);

clonidine (Catapres);

reserpine; or

beta-blockers including atenolol (Tenormin), carvedilol (Coreg), metoprolol (Lopressor, Toprol), propranolol (Inderal, InnoPran), among others.

You could possibly be very likely to have hyperglycemia (high blood sugar levels) in the event you take glyburide with:


diuretics (water pills);

steroids (prednisone yet others);

phenothiazines (Compazine and others);

thyroid medicine (Synthroid yet others);

birth control pills as well as other hormones;

heart or blood pressure medications (Cartia, Cardizem, Nifedical, Covera, Verelan, while others);

niacin (Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, and others);

seizure medicines (Dilantin while others); and

diet pills or medicines to treat asthma, colds or allergies.

You might be prone to have hypoglycemia (low blood sugar levels) in the event you take glyburide with:

clarithromycin (Biaxin);

exenatide (Byetta);

probenecid (Benemid);

heart or blood pressure levels medication (Accupril, Altace, Lotensin, Prinivil, Vasotec, Zestril, while others);

some nonsteroidal anti-inflammatory drugs (NSAIDs);

aspirin or another salicylates (including Pepto-Bismol);

sulfa drugs (Bactrim, Gantanol, Septra, yet others);

a monoamine oxidase inhibitor (MAOI); and

other oral diabetes medications, especially acarbose (Precose), metformin (Glucophage), miglitol (Glyset), pioglitazone (Actos), or rosiglitazone (Avandia).

These lists are certainly not complete and you can find many other medicines that will increase or say goodbye of glyburide on cutting your blood sugar. Tell your physician about all medications you utilize. This includes prescription, over-the-counter, vitamin, and herbal products. Do not begin a new medication without telling your medical professional.


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