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Precautions

Do NOT use Metoclopramide if:

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• you happen to be allergic to the ingredient in Metoclopramide

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• you might have seizures (eg, epilepsy); bleeding, blockage, or perforation inside your stomach or intestines; or tumors on the adrenal gland (pheochromocytoma)

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• you take cabergoline or pergolide

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• you consider medicines, including phenothiazines (eg, chlorpromazine), that might cause extrapyramidal reactions (abnormal, involuntary muscle movements from the head, neck, or limbs). Check with your physician in case you are unsure if any medicines might cause extrapyramidal reactions.

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Contact your medical professional or health care provider straight away if all of these connect with you.

Some health conditions may talk with Metoclopramide. Tell your medical professional or pharmacist when you have any health concerns, particularly when any in the following connect with you:

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• should you be pregnant, intending to become pregnant, or are breast-feeding

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• if you consider any prescription or nonprescription medicine, herbal preparation, or dietary supplement

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• for those who have allergies to medicines, foods, or other substances

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• when you have a good reputation for mental or mood problems (eg, depression) or suicidal thoughts or actions

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• if you have a reputation asthma, heart failure, blood pressure, diabetes, Parkinson disease, blood problems (eg, porphyria), kidney problems, liver problems (eg, cirrhosis), breast cancer, or low levels associated with an enzyme called methemoglobin reductase

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• if you are taking another form of metoclopramide (eg, syrup, orally disintegrating tablet).

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Some medicines may communicate with Metoclopramide. Tell your doctor should you consider another medicines, especially any with the following:

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• Monoamine oxidase inhibitors (MAOIs) (eg, phenelzine) because the risk of serious negative effects (eg, high blood pressure, seizures) might be increased

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• Anticholinergic medicine (eg, hyoscyamine) or narcotic pain medicines (eg, codeine) because they may decrease Metoclopramide's effectiveness

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• Acetaminophen, benzodiazepines (eg, diazepam), cyclosporine, insulin, levodopa, phenothiazines (eg, chlorpromazine), sedatives (eg, zolpidem), selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine), succinylcholine, or tetracycline for the reason that chance of their negative effects could possibly be increased by Metoclopramide

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• Cabergoline, digoxin, or pergolide because their effectiveness could possibly be decreased by Metoclopramide.

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This is probably not a total report on all interactions that will occur. Ask your doctor if Metoclopramide may connect to other medicines that you simply take. Check with your doctor before you start, stop, or affect the dose of the medicine.

Important safety information:

• Metoclopramide may cause drowsiness or dizziness. These effects may be worse should you get it with alcohol or certain medicines. Use Metoclopramide with caution. Do not drive or perform other possible unsafe tasks before you know how you reply to it.
• Do not drink alcohol or use medicines that might cause drowsiness (eg, sleep aids, muscle relaxers) while you're using Metoclopramide without first checking with your medical professional; it may help to increase their effects. Ask your friendly phamacist when you have queries about which medicines might cause drowsiness.

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• Do NOT take a lot more than the recommended dose or use Metoclopramide for more than 12 weeks without checking using your doctor.

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• Diabetes patients - Metoclopramide may affect your blood glucose levels. Check blood glucose levels closely. Ask a medical expert prior to deciding to change the dose of the diabetes medicine.

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• Tell your physician or dentist that you simply take Metoclopramide before you get any medical or dental treatments, emergency care, or surgery.
• Neuroleptic malignant syndrome (NMS) is often a possibly fatal syndrome that can be caused by Metoclopramide. Symptoms may include fever; stiff muscles; confusion; abnormal thinking; fast or irregular heartbeat; and sweating. Contact your doctor immediately if you have these symptoms.

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• Some patients having Metoclopramide may develop muscle movements that they can cannot control. This is very likely to happen in elderly patients, especially women. The chance this will happen or that it will become permanent is greater in those taking Metoclopramide in higher doses and for quite a while. Muscle problems may also occur after short-term treatment with low doses. Tell a medical expert at once if you have muscle problems with your arms; legs; or maybe your tongue, face, mouth, or jaw (eg, tongue herniated, puffing of cheeks, mouth puckering, chewing movements) while taking Metoclopramide.
• Patients taking Metoclopramide might be at increased risk for first time or worsening mental or mood changes (eg, depression) or suicidal thoughts or actions. Watch patients having Metoclopramide closely. Contact the physician at the same time if new, worsened, or sudden symptoms including depressed mood or any unusual difference in mood or behavior occur. Contact the doctor straight away if any signs of suicidal thoughts or actions occur.
• Metoclopramide might increase the amount of a certain hormone (prolactin) with your blood. Symptoms can sometimes include enlarged breasts, missed monthly period, decreased sexual ability, or nipple discharge. Contact a medical expert straight away in case you experience some of these symptoms.

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• Lab tests, including liver and kidney function tests, may be performed as you use Metoclopramide. These tests may be used to monitor your trouble or look for negative effects. Be sure to hold all doctor and lab appointments.

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• Use Metoclopramide with caution in the elderly; they might be more sensitive to its effects, especially drowsiness, confusion, and uncontrolled muscle movements, including tardive dyskinesia.
• Metoclopramide ought to be combined with extreme caution in youngsters; safety and effectiveness in kids weren't confirmed. The likelihood of developing uncontrolled muscle movements may be greater in youngsters.

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• Pregnancy and breastfeeding: If you conceive, contact your medical professional. You will need to discuss the benefits and perils of using Metoclopramide while you are pregnant. Metoclopramide is situated in breast milk. If you're or will be breast-feeding as you use Metoclopramide, check with your doctor. Discuss any possible risks for a baby.

A small number of patients have seen withdrawal symptoms when stopping Metoclopramide. These symptoms may include dizziness, nervousness, and headache.

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