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Mestinon (Pyridostigmine) affects chemicals in your body which can be mixed up in communication between nerve impulses and muscle movement.

Pyridostigmine is utilized to deal with the signs and symptoms of myasthenia gravis. It is also utilized in military personnel who had been subjected to nerve gas.

Pyridostigmine could also be used for purposes unpublished in this medication guide.


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Take exactly as prescribed through your doctor. Do not take in larger or smaller amounts or for over recommended. Follow the directions in your prescription label.
Take this medicine with food or milk if it upsets your stomach. Do not crush, chew, or break an extended-release tablet. Swallow it whole. Breaking or opening the pill may cause excessive drug to be removed at once.

Measure liquid medicine having a special dose measuring spoon or medicine cup, not using a regular table spoon. If you do not have a dose measuring device, ask your friendly phamacist for starters.

The amount and timing of the drugs are very important for the success of your respective treatment. Carefully follow your physician's instructions about how exactly much medicine to consider then when to look at it.

Your doctor may occasionally improve your dose to ensure that you receive the best results. You may be inspired to keep a daily record of whenever you took each dose and just how long the consequences lasted. This will help your doctor determine whether your dose has to be adjusted.
If you need surgery, tell the surgeon in advance that you are using pyridostigmine. You may need to stop with all the medicine for any small amount of time. Store at room temperature from moisture and also heat.


Take the medicine as prescribed by your doctor.


Keep the tablets of their original container, along with the canister of moisture-absorbing preservative that accompanies this medicine.

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Active ingredient: Pyridostigmine

Side Effects

Get emergency medical help for those who have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of one's face, lips, tongue, or throat. Stop using pyridostigmine and call your doctor at once in case you have all of these serious unwanted effects:

extreme muscle weakness, muscle twicthing;

slurred speech, vision problems;

severe vomiting or diarrhea;

cough with mucus;

confusion, anxiety, anxiety attacks;

seizure (convulsions); or

worsening or no improvement with your symptoms of myasthenia gravis.

Less serious side effects can include:

cold sweat, pale skin;

urinating more than usual;

watery eyes;

mild nausea, vomiting, or upset stomach;

warmth or tingly feeling; or

mild rash or itching.

This isn't a complete listing of side effects among others may occur. Call your medical professional for health advice about unwanted side effects.

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You should not use pyridostigmine if you are allergic to it, or if you possess a bladder or bowel obstruction.

To make sure you can safely take pyridostigmine, tell your physician in case you have these other concerns:


kidney disease;

an ulcer or another serious stomach disorder;

high blood pressure, coronary disease;

overactive thyroid; or

a good seizures.

It just isn't known whether pyridostigmine will harm an developing fetus. Tell your doctor in case you are pregnant or want to become pregnant while using the prescription drugs. It is just not known whether pyridostigmine passes into breast milk or whether or not this could harm a nursing baby. Do not use medicines without telling your doctor if you are breast-feeding a baby.

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Drugs interaction 

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Tell your doctor about all the other medicines you employ, especially:

atropine (Atreza, Sal-Tropine);

belladonna (Donnatal, yet others);

benztropine (Cogentin);

clidinium (Quarzan);

clozapine (Clozaril, FazaClo);

dimenhydrinate (Dramamine);

methscopolamine (Pamine), scopolamine (Transderm Scop);

glycopyrrolate (Robinul);

mepenzolate (Cantil);

bladder or urinary medications for example darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare);

bronchodilators including ipratropium (Atrovent) or tiotropium (Spiriva);

cold medicine, allergy medicine, or sleeping pills that contain an antihistamine like diphenhydramine (Tylenol PM) or doxylamine (Unisom);

heart rhythm medication such as quinidine (Quin-G), procainamide (Procan, Pronestyl), disopyramide (Norpace), flecaininde (Tambocor), mexiletine (Mexitil), propafenone, (Rythmol), while others;

irritable bowel medications for example dicyclomine (Bentyl), hyoscyamine (Hyomax), or propantheline (Pro Banthine);

medicine to help remedy Alzheimer's dementia, including donepezil (Aricept), rivastigmine (Exelon), or tacrine (Cognex); or

a steroid such as betamethasone (Celestone) or dexamethasone (Cortastat, Dexasone, Solurex, DexPak).

This list just isn't complete and other drugs may communicate with pyridostigmine. Tell a medical expert about all medications you utilize. This includes prescription, over-the-counter, vitamin, and herbal products. Do not begin a new medication without telling a medical expert.

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