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Uses

INDICATIONS

Keppra can be used to take care of partial onset seizures in adults and youngsters who are at least four weeks old.
It can also be used to take care of tonic-clonic seizures in older adults and kids who are at the very least 6 years old, and myoclonic seizures in older adults and children who will be at least 12 years old.

INSTRUCTIONS

Take Keppra just as prescribed because of your doctor. Do not take in larger or smaller amounts and for over recommended. Follow the directions on the prescription label.

Your doctor may occasionally make positive changes to dose to ensure that you obtain the best results.

Keppra is generally taken twice per day. Take the medicine simultaneously each day. You may take Keppra with or without food.

Measure liquid medicine using a special dose-measuring spoon or medicine cup, not using a regular table spoon. If you do not have a very dose-measuring device, ask the pharmacist first.
Do not crush, chew, or break a controlled release, delayed-release, or extended-release tablet. Swallow it whole. Breaking the pill may cause a lot of drug to be released previously.

Use Keppra regularly to find the most benefit. Get your prescription refilled before you run out of drugs completely.

Do not stop using Keppra without first actually talking to your medical professional, even though you feel great. You may have increased seizures in the event you stop by using this medicine suddenly. You should use less before you stop the medication completely.

Seizures will often be treated having a combination of different drugs. Use all medications as directed because of your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice. .

Wear a medical alert tag or carry an ID card praoclaiming that you're taking Keppra. Any health care provider who treats you should know that you take seizure medication.

To make certain Keppra is just not causing harmful effects, your kidney function might need to be tested. Visit a medical expert regularly.

If you missed a dose - take the missed dose whenever you remember. Skip the missed dose whether it is almost time for your forthcoming scheduled dose. Do not take extra medicine to make the missed dose.

DOSAGE

Important Administration Instructions

Keppra is given orally with or without food. The Keppra dosing regimen depends on the indication, generation, dosage form (tablets or oral solution), and renal function.

Prescribe the oral solution for pediatric patients with body mass ≤ 20 kg. Prescribe the oral solution or tablets for pediatric patients with bodyweight above 20 kg.

When while using oral solution in pediatric patients, dosing is weight-based (mg per kg) using a calibrated measuring device (not a household teaspoon or tablespoon).
Keppra tablets needs to be swallowed whole. Keppra tablets really should not be chewed or crushed.

Pediatric Patients

Treatment must be initiated with a daily dose of 14 mg/kg by 50 % divided doses (7 mg/kg two tmes a day). The daily dose needs to be increased every two weeks by increments of 14 mg/kg on the recommended daily dose of 42 mg/kg (21 mg/kg twice daily). In the clinical trial, the mean daily dose was 35 mg/kg on this generation. The effectiveness of lower doses has not been studied.

Treatment must be initiated with a daily dose of 20 mg/kg into two divided doses (10 mg/kg twice a day). The daily dose must be increased by 50 % weeks by an increment of 20 mg/kg on the recommended daily dose of 50 mg/kg (25 mg/kg two tmes a day). If a patient cannot tolerate an everyday dose of 50 mg/kg, the daily dose may be reduced. In the clinical study, the mean daily dose was 47 mg/kg on this population.

Treatment should be initiated which has a daily dose of 20 mg/kg in 2 divided doses (10 mg/kg twice a day). The daily dose must be increased every 14 days by increments of 20 mg/kg for the recommended daily dose of 60 mg/kg (30 mg/kg twice a day). If a patient cannot tolerate a regular dose of 60 mg/kg, the daily dose might be reduced. In the clinical efficacy trial, the mean daily dose was 44 mg/kg. The maximum daily dose was 3000 mg/day.

For Keppra tablet dosing in pediatric patients weighing 20 to 40 kg, treatment needs to be initiated having a daily dose of 500 mg given as twice a day dosing (250 mg two times a day). The daily dose needs to be increased every 2 weeks by increments of 500 mg with a maximum recommended daily dose of 1500 mg (750 mg two times a day).

For Keppra tablet dosing in pediatric patients weighing greater than 40 kg, treatment should be initiated with a daily dose of 1000 mg/day given as twice daily dosing (500 mg two times a day). The daily dose must be increased every fourteen days by increments of 1000 mg/day to some maximum recommended daily dose of 3000 mg (1500 mg twice a day).


Partial Onset Seizures
Adults 16 Years And Older

In clinical trials, daily doses of 1000 mg, 2000 mg, and 3000 mg, given as twice-daily dosing were confirmed to be effective. Although in some studies there were an inclination toward greater response with higher dose [see Clinical Studies], an even increase in response with additional dose will not be shown.

Treatment must be initiated having a daily dose of 1000 mg/day, given as twice-daily dosing (500 mg twice daily). Additional dosing increments may be given (1000 mg/day additional every 2 weeks) to some maximum recommended daily dose of 3000 mg. Doses higher than 3000 mg/day are actually utilized in open-label studies for periods of 6 months and longer. There is no evidence that doses greater than 3000 mg/day confer additional benefit.

Myoclonic Seizures In Patients 12 Years of Age and Older With Juvenile Myoclonic Epilepsy
Treatment ought to be initiated with a dose of 1000 mg/day, given as twice-daily dosing (500 mg twice a day). Dosage must be increased by 1000 mg/day every two weeks to the recommended daily dose of 3000 mg. The effectiveness of doses less than 3000 mg/day will not be studied.


Primary Generalized Tonic-Clonic Seizures
Adults 16 Years And Older
Treatment must be initiated having a dose of 1000 mg/day, given as twice-daily dosing (500 mg twice daily). Dosage must be increased by 1000 mg/day every two weeks for the recommended daily dose of 3000 mg. The effectiveness of doses less than 3000 mg/day will not be adequately studied.


Pediatric Patients Ages 6 To < 16 Years
Treatment ought to be initiated having a daily dose of 20 mg/kg in 2 divided doses (10 mg/kg two times a day). The daily dose needs to be increased every two weeks by increments of 20 mg/kg on the recommended daily dose of 60 mg/kg (30 mg/kg two times a day). The effectiveness of doses less than 60 mg/kg/day has not been adequately studied. Patients with bodyweight ≤ 20 kg must be dosed with oral solution. Patients with weight above 20 kg may be dosed with either tablets or oral solution. Only whole tablets needs to be administered.


Adult Patients With Impaired Renal Function
Keppra dosing has to be individualized according for the patient's renal function status.

STORAGE

Store Keppra at room temperature away from moisture, heat, and light.

Side Effects

Get emergency medical help if you have any of these signs and symptoms of an allergic reaction to Keppra: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Report any new or worsening symptoms to your medical professional, for example: mood or behavior changes, depression, anxiety, or in case you feel agitated, hostile, irritable, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Call your physician simultaneously should you use a serious complication like:

Less serious Keppra unwanted effects can sometimes include:

This just isn't a complete list of side effects while others may occur. Tell your medical professional about any unusual or bothersome side-effect.

Precautions

You should not use Keppra should you are allergic to levetiracetam.

To make sure you can safely take Keppra, tell your medical professional in case you have kidney disease or high blood pressure.

You could possibly have thoughts about suicide while investing in this medicine. Tell your physician in case you have signs of depression or suicidal thoughts through the first a few months of treatment, or once your dose is changed.

Your family and other caregivers should also be alert to changes in your mood or symptoms. Your doctor will have to check you at regular visits.

FDA pregnancy category C. It is not known whether Keppra will harm an developing fetus, but developing a seizure in pregnancy could harm the mother along with the baby. Tell your medical professional if you are pregnant or want to conceive while using this medication. Do not start or stop taking Keppra during pregnancy without a medical expert's advice. Seizure control is vital during pregnancy. The benefit of preventing seizures may outweigh any risks posed by taking Keppra. Follow your physician's instructions about taking Keppra when you are pregnant. Levetiracetam can pass into breast milk and may even harm a nursing baby. You should not breast-feed if you are using Keppra. Do not give medicines to some child with no advice of an doctor. Your child's dose needs are based on age and weight. The child should remain within the care of your doctor while employing this medicine.

Do not stop using Keppra without first conversing with your doctor, even if you feel great. You could possibly have increased seizures in the event you stop using Keppra suddenly. You should use less and less before you decide to stop the medication completely.

You could have thoughts about suicide while taking Keppra. Your doctor should check you at regular visits. Do not miss any scheduled appointments.

Report any new or worsening symptoms to your physician, such as: mood or behavior changes, depression, anxiety, or in case you feel agitated, hostile, irritable, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Wear a medical alert tag or carry an ID card proclaiming that you're taking Keppra. Any health care bills provider who treats you need to know that you take seizure medication.

Keppra may impair your notions or reactions. Be careful in the event you drive or do just about anything that will need you to definitely be alert. Tell your medical professional should you are pregnant or plan to get pregnant while using this medication. Do not start or stop taking Keppra during pregnancy without your medical professional's advice. Having a seizure when pregnant could harm both the mother along with the baby. Seizure control is vital in pregnancy and the great things about preventing seizures may outweigh any risks posed by using Keppra.

Avoid drinking alcohol. It can increase many of the unwanted side effects of Keppra and might could also increase the potential risk of seizures. This medication may impair your thinking or reactions. Be careful in case you drive or do just about anything that will need one to be alert.


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