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Precautions

Do NOT use Isoniazid if:

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• you're allergic to any ingredient in Isoniazid or also have severe unwanted side effects from isoniazid, for example drug fever, chills, or arthritis

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• you've severe liver damage, active liver disease, or liver damage from previous use of Isoniazid

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Contact your physician or physician without delay if all of these sign up for you.

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Some health conditions may talk with Isoniazid. Tell a medical expert or pharmacist for those who have any health conditions, particularly if any with the following apply to you:

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• if you are pregnant, about to become pregnant, or are breast-feeding

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• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

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• in case you have allergies to medicines, foods, or another substances
• if you have diabetes, kidney problems, nerve problems (eg, neuropathy) or likelihood of nerve problems, HIV, or possibly a good reputation for liver problems

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• if you use a good alcohol and other substance abuse, have unsanitary injectable drug habits, or are drinking alcohol daily
• if you are much older than 35 years old, you have recently given birth, or you might have previously taken Isoniazid.

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Some medicines may connect to Isoniazid. Tell your health care provider if you're taking some other medicines, especially any of the following:

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• Acetaminophen, anticoagulants (eg, warfarin), carbamazepine, hydantoins (eg, phenytoin), rifampin, theophylline, or valproic acid as the risk of their negative effects may be increased by Isoniazid
• Ketoconazole because its effectiveness may be decreased by Isoniazid.

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This will not be a complete set of all interactions which could occur. Ask your medical provider if Isoniazid may talk with other medicines that you take. Check with your medical provider before you begin, stop, or change the dose associated with a medicine.

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• Check along with your doctor before drinking alcohol with all the Isoniazid. Alcohol could raise the probability of liver problems. If you have a very history of alcohol abuse, you can also be at increased likelihood of developing nerve problems from Isoniazid. Notify your doctor if you see any unusual tingling or numbness up to you or feet.
• If you have a very good reputation for diabetes, alcohol abuse, or poor nutrition, your physician may recommend that you also take vitamin B₆ while you might be taking Isoniazid. This may help decrease your likelihood of nerve problems. Discuss any queries with your medical professional.

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• Do not eat foods an excellent source of tyramine while you use Isoniazid. Eating foods high in tyramine (eg, aged cheeses, red wines, beer, certain meats and sausages, liver, sour cream, soy sauce, raisins, bananas, avocados) whilst you use Isoniazid might cause severe high hypertension. Seek medical help at once if the signs of severe high blood pressure occur. These may include severe headache, fast or irregular heartbeat, sore or stiff neck, nausea, vomiting, sweating, enlarged pupils, or sensitivity to light.

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• Do not eat foods high in histamine while you use Isoniazid. Eating foods full of histamine (eg, skipjack, tuna, tropical fish) whilst you use Isoniazid could potentially cause low blood pressure levels, irregular heartbeat, headache, sweating, or flushing. Contact your physician simultaneously if some of these symptoms occur.

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• Ask your medical provider for the complete list of all foods you ought to avoid while you are using Isoniazid.

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• Isoniazid only works against TB bacteria; it won't treat viral infections (eg, the regular cold).

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• Be sure to use Isoniazid for that full course of treatment. If you do not, the medicine might not clear up your infection completely. The bacteria may also become less sensitive to this and other medicines. This could make infection harder to take care of in the long run.

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• Diabetes patients - Isoniazid may affect your blood sugar levels. Check blood glucose levels closely. Ask your medical professional before you change the dose of your respective diabetes medicine. You can also be at increased likelihood of developing nerve problems from Isoniazid. Contact your doctor possibly any unusual tingling with you or feet.
• Lab tests, including liver function and eye exams, could possibly be performed whilst you use Isoniazid. These tests may be used to observe your condition or look for side effects. Be sure to keep all doctor and lab appointments.

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• Pregnancy and breast-feeding: If you become pregnant, speak to your doctor. You will need to discuss the benefits and perils of using Isoniazid while you're pregnant. Isoniazid is found in breast milk. If you happen to be or will be breast-feeding while you use Isoniazid, check using your doctor. Discuss any possible risks to your child.

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