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Precautions

Do NOT use Estrace if:

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• you are allergic to the ingredient in Estrace

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• you are pregnant or suspect you may well be pregnant, have recently given birth or are breast-feeding, or have vaginal bleeding of abnormal or unknown cause

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• you've got known or suspected cancer of the breast (unless directed by your doctor) or else you have cancers which can be estrogen-dependent

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• you have blood clots, vein inflammation, or liver disease

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• you have had a recently available stroke or heart attack.

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Contact your physician or health care provider straight away if these affect you.

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Some medical conditions may communicate with Estrace. Tell a medical expert or pharmacist in case you have any health concerns, particularly when any from the following connect with you:

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• if you're planning to become pregnant

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• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

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• if you have allergies to medicines, foods, or another substances

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• if you have a genealogy and family history of breast cancer, or you have breast lumps or disease, or perhaps an abnormal mammogram

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• when you have yellowing in the whites from the eyes or skin during pregnancy or with past estrogen use, or high blood pressure levels when pregnant (toxemia)

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• when you have a vaginal infection or womb problems (eg, uterine fibroids/endometriosis, abnormal vaginal bleeding, other uterine problems)
• if you have abnormal calcium levels within the blood, asthma, cancer, certain blood disorder (porphyria), cholesterol or lipid problems, depression, diabetes, epilepsy, excessive extra weight, gallbladder disease, cardiovascular disease or other heart disease, blood pressure, kidney or liver disease, low thyroid hormonal levels, lupus, migraines, pancreas disease, seizures, or yellowing of the skin or eyes
• in case you smoke or will be having surgery.

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Some medicines may interact with Estrace. Tell your health care provider if you take another medicines, especially any of the following:

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• Blood thinners (eg, warfarin), corticosteroids (eg, prednisone), succinylcholine, or tacrine because their actions and the probability of their side effects may be increased by Estrace

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• Blood thinners (eg, warfarin) his or her effectiveness might be decreased by Estrace
• Barbiturates (eg, phenobarbital), hydantoins (eg, phenytoin), or rifampin simply because they may decrease Estrace's effectiveness.

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This will not be a whole set of all interactions that will occur. Ask your doctor if Estrace may connect to other medicines that you simply take. Check with your doctor before you begin, stop, or affect the dose of the medicine.

Important safety information:

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• Estrace could potentially cause dizziness. This effect may be worse should you get it with alcohol or certain medicines. Use Estrace with caution. Do not drive or perform other possible unsafe tasks before you recognize how you answer it.

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• Limit alcoholic beverages if you are taking Estrace.
• Estrace may cause dark skin patches on the face (melasma). Exposure for the sun will make these patches darker and you will need to avoid prolonged sun damage and sunlamps. Consult your medical professional in connection with utilization of sunscreens and protective clothing.

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• Estrace may increase the likelihood of blood clots. The risk may be greater if you smoke (especially in women much older than 35 years old).

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• Contact your physician if vaginal bleeding of unknown cause occurs. This could be a sign of a critical condition requiring immediate medical assistance.

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• Contact your physician if vaginal discomfort occurs or should you suspect you might have developed disease while taking Estrace.
• Follow your physician's instructions for examining your breasts and report any lumps immediately.
• Additional monitoring of your respective dose or condition may be necessary should you be presently taking an azole antifungal (eg, itraconazole), carbamazepine, a macrolide antibiotic (eg, erythromycin), ritonavir, cimetidine, or St. John's wort.

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• If you wear contact lenses and you also develop issues with them, contact your doctor.
• If you will likely be having surgical procedures or will be restricted to a chair or bed for a long period of your energy (eg, a good plane flight), notify a medical expert beforehand. Special precautions may must be used in these circumstances if you are taking Estrace.
• Nonprescription therapy to aid prevent bone loss includes a weight-bearing exercise program, and also adequate daily calcium and vitamin D intake. Consult your doctor or pharmacist for more details.

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• Some of these products could have the dye tartrazine (FD&C Yellow No. 5), which could cause allergies in a few patients. Consult a medical expert or pharmacist. If you previously had allergic reactions to the dye tartrazine, contact your doctor or pharmacist to determine if the product you take provides the dye tartrazine.

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• Estrace may interfere with certain lab tests. Be sure your doctor and lab personnel know you take Estrace.

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• Diabetes patients - Estrace may affect your blood glucose. Check blood glucose levels levels closely. Ask your doctor prior to deciding to alter the dose of one's diabetes medicine.
• Lab tests, including physical exams and hypertension, could possibly be performed as you use Estrace. You should have breast and pelvic exams, along with a Pap test at least 12 months. You should also have periodic mammograms as determined because of your doctor. Be sure to keep all doctor and lab appointments.

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• Estrace should not be used in children; safety and effectiveness in kids are not confirmed.
• Pregnancy and breast-feeding: Do not use Estrace if you're pregnant. Avoid pregnancy while you're taking it. If you think you may be pregnant, contact your doctor immediately. Estrace could possibly be found in breast milk. If you are or will probably be breast-feeding as you use Estrace, check along with your doctor. Discuss any possible risks for a baby.

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