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Precautions

Do NOT use Estrace if:

• you are allergic to your ingredient in Estrace
• you are pregnant or suspect you might be pregnant, have recently given birth or are breast-feeding, or have vaginal bleeding of abnormal or unknown cause
• you've known or suspected breast cancer (unless directed by your doctor) or you have cancers which might be estrogen-dependent
• you've got blood clots, vein inflammation, or liver disease
• you also have a current stroke or cardiac event.

Contact your physician or doctor right away if these apply to you.

Some health conditions may interact with Estrace. Tell your medical professional or pharmacist if you have any health concerns, particularly if any of the following connect with you:

• if you're planning to become pregnant
• if you take any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• in case you have allergies to medicines, foods, or any other substances
• when you have a ancestors and family history of breast cancer, or you have breast lumps or disease, or an abnormal mammogram
• if you have yellowing from the whites from the eyes or skin during pregnancy or with past estrogen use, or blood pressure in pregnancy (toxemia)
• for those who have a vaginal infection or womb problems (eg, uterine fibroids/endometriosis, abnormal vaginal bleeding, other uterine problems)
• for those who have abnormal calcium levels inside the blood, asthma, cancer, certain blood disorder (porphyria), cholesterol or lipid problems, depression, diabetes, epilepsy, excessive fat gain, gallbladder disease, heart problems and other cardiovascular disease, high blood pressure levels, kidney or liver disease, low thyroid hormone levels, lupus, headaches, pancreas disease, seizures, or yellowing of the skin or eyes
• if you smoke or is going to be having surgery.

Some medicines may interact with Estrace. Tell your doctor if you are taking some other medicines, especially any from the following:

• Blood thinners (eg, warfarin), corticosteroids (eg, prednisone), succinylcholine, or tacrine as their actions as well as the risk of their negative effects might be increased by Estrace
• Blood thinners (eg, warfarin) his or her effectiveness may be decreased by Estrace
• Barbiturates (eg, phenobarbital), hydantoins (eg, phenytoin), or rifampin because they may decrease Estrace's effectiveness.

This is probably not a complete listing of all interactions which could occur. Ask your health care provider if Estrace may interact with other medicines which you take. Check with your medical provider before you begin, stop, or affect the dose of any medicine.

Important safety information:

• Estrace could cause dizziness. This effect might be worse in case you go on it with alcohol or certain medicines. Use Estrace with caution. Do not drive or perform other possible unsafe tasks until you recognize how you respond to it.
• Limit alcohol consumption if you are taking Estrace.
• Estrace could potentially cause dark skin patches on the face (melasma). Exposure to the sun may make these patches darker and you might should avoid prolonged exposure to the sun and sunlamps. Consult your doctor about the use of sunscreens and protective clothing.
• Estrace may increase the likelihood of blood clots. The risk could possibly be greater in the event you smoke (especially in women more than 35 years old).
• Contact your physician if vaginal bleeding of unknown cause occurs. This could be a sign of a life threatening condition requiring immediate medical help.
• Contact your physician if vaginal discomfort occurs or in case you suspect you might have developed contamination while taking Estrace.
• Follow a medical expert's instructions for examining your breasts and report any lumps immediately.
• Additional monitoring of your dose or condition could possibly be necessary should you be presently taking an azole antifungal (eg, itraconazole), carbamazepine, a macrolide antibiotic (eg, erythromycin), ritonavir, cimetidine, or St. John's wort.
• If you wear contact lenses and you develop issues with them, get hold of your doctor.
• If you is going to be having surgery or is going to be restricted to a chair or bed for long periods of time (eg, a long plane flight), notify your doctor beforehand. Special precautions may must be studied of these circumstances when you are taking Estrace.
• Nonprescription therapy to aid prevent bone loss features a weight-bearing fitness plan, and also adequate daily calcium and vitamin D intake. Consult your medical professional or pharmacist for additional information.
• Some of the products could have the dye tartrazine (FD&C Yellow No. 5), which may cause allergies in a few patients. Consult a medical expert or pharmacist. If you previously had allergic reactions on the dye tartrazine, speak to your doctor or pharmacist to ascertain if the product you adopt contains the dye tartrazine.
• Estrace may hinder certain diagnostic tests. Be sure your doctor and lab personnel know you're taking Estrace.
• Diabetes patients - Estrace may affect your blood sugar levels. Check blood sugar levels levels closely. Ask your physician prior to deciding to alter the dose of the diabetes medicine.
• Lab tests, including physical exams and blood pressure levels, might be performed whilst you use Estrace. You should have breast and pelvic exams, and a Pap test at least one time per year. You should also have periodic mammograms as determined because of your doctor. Be sure to keep all doctor and lab appointments.
• Estrace shouldn't be used in children; safety and effectiveness in children have not been confirmed.
• Pregnancy and breast-feeding: Do not use Estrace if you're pregnant. Avoid becoming pregnant when you are taking it. If you think you may well be pregnant, get hold of your doctor immediately. Estrace could be within breast milk. If you are or will probably be breast-feeding when you use Estrace, check with your doctor. Discuss any possible risks for a baby.