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Eldepryl is indicated as an adjunct inside the control over Parkinsonian patients receiving care with levodopa/carbidopa who exhibit deterioration within the quality of these response to this therapy.


Take this medicine only as directed by your doctor. Do not take a greater portion of it, don't take on it more frequently, and don't take it for a longer time than your doctor ordered.

It is better to consider this medicine before breakfast and without liquids.

If you are while using the disintegrating tablet, make sure your hands are dry before you decide to handle today. Do not open the blister pack made up of these days until you're ready to take it. Remove these days from your blister pack by peeling back the foil, then taking today out. Do not push the tablet from the foil. Do not break or split today. Place the tablet for the top of your tongue, where it'll melt quickly. Do not eat food or drink liquids for 5 minutes before or after using this medicine.

If you miss a dose of this medicine, go at the earliest opportunity. However, if it is almost time for your next dose, skip the missed dose and return to your family dosing schedule. Do not double doses.


The dose on this medicine will change many different patients. Follow your medical professional's orders or the directions on the label. The following information includes only the average doses on this medicine. If your dose differs, do not put it back unless a medical expert informs you for this.

The level of medicine that you simply take depends on the strength in the medicine. Also, the amount of doses you're taking on a daily basis, time allowed between doses, and the period of time you take the medicine depend about the problem for which you're while using the medicine.
For oral dosage form (tablets):
For Parkinson's disease:


Store the medicine inside a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep from the reach of kids.
Do not keep outdated medicine or medicine no longer needed.

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Eldepryl is often a levorotatory acetylenic derivative of phenethylamine. It is commonly known as inside the clinical and pharmacological literature as l-deprenyl.

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Side Effects

Along having its needed effects, medicine could cause some unwanted side effects. Although not most of these unwanted effects may occur, should they occur they might need medical assistance.

Check with your physician immediately if the following negative effects occur:

More common
Chest pain (severe)
enlarged pupils
fast or slow heartbeat
headache (severe)
increase in unusual movements in the body
increased sensitivity in the eyes to light
increased sweating (possibly with fever or cold, clammy skin)
mood and other mental changes
nausea and vomiting (severe)
stiff or sore neck

Less common or rare
Bloody or black, tarry stools
convulsions (seizures)
decreased urine
difficult or frequent urination
difficulty with breathing
difficulty with speaking
difficulty with swallowing
dizziness or lightheadedness, especially when arising coming from a lying or sitting position
dry mouth
hallucinations (seeing, hearing, or feeling items that are not there)
increased thirst
irregular heartbeat
large, flat, blue, or purplish patches within the skin
lip smacking or puckering
loss of appetite
loss of balance control
muscle pain or cramps
nausea or vomiting
numbness or tingling inside hands, feet, or lips
puffing with the cheeks
rapid or worm-like movements of the tongue
restlessness or wish to keep moving
severe stomach pain
shakiness within the legs, arms, hands, or feet
shortness of breath
swelling with the feet or lower legs
swelling or inflammation of the mouth
tightness inside the chest
trembling or shaking from the hands or feet
twisting movements from the body
uncontrolled chewing movements
uncontrolled movements in the face, neck, back, arms, or legs
unusual tiredness or weakness
vomiting of blood or material that looks like coffee grounds

Get emergency help immediately if these things signs and symptoms of overdose occur:

Symptoms of overdose
Agitation or irritability
chest pain
difficulty opening the mouth or lockjaw
dizziness (severe) or fainting
fast or irregular pulse (continuing)
high fever
high or low blood pressure
severe spasm the place that the head and heels are bent backward and also the body arched forward
troubled breathing

Some negative effects may occur that always do not need medical attention. These unwanted side effects may go away during treatment as your body adjusts towards the medicine. Also, your quality of life care professional may be able to let you know about methods to prevent or reduce a few of these unwanted side effects. Check with your health care professional if the following negative effects continue or are bothersome or if you might have questions about them:

More common
Abdominal or stomach pain
dizziness or feeling faint
runny nose
stuffy nose
trouble with sleeping

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Less common or rare
back or leg pain
blurred or double vision
body aches or pain
burning of the lips, mouth, or throat
dryness or soreness in the throat
frequent urge to urinate
inability to move
increased sweating
irritability (temporary)
memory problems
pounding or fast heartbeat
red, raised, or itchy skin
ringing or buzzing in the ears
slow or difficult urination
slowed movements
taste changes
uncontrolled closing of the eyelids
unusual a feeling of well-being
unusual weight loss
voice changes

Other unwanted effects not listed may also appear in some patients. If you notice any other effects, check with your healthcare professional.


It is critical that your physician look at your progress at regular visits to allow for alterations in your dose and also to pay attention to any unwanted effects.

Do not take selegiline if you might have used meperidine (e.g., Demerol®) or an MAO inhibitor (MAOI) (e.g., isocarboxazid, phenelzine, tranylcypromine, Marplan®, Nardil®, or Parnate®) within the past 14 days. If you do, you might develop agitation, confusion, restlessness, stomach or intestinal symptoms, sudden high temperature, higher than normal blood pressure levels, or severe convulsions.

Do not take cough medicines (e.g., dextromethorphan, Robitussin®, Pediacare®) or pain medicines (e.g., methadone, propoxyphene, tramadol, Darvon®, Dolophine®, Ultram®) while you are using this medicine. Using these medicines together may cause uncomfortable side effects.

Selegiline might cause serious unwanted effects when used in addition to some antidepressants. Tell your physician if you've got used amitriptyline, doxepin, fluoxetine, fluvoxamine, nortriptyline, paroxetine, sertraline, Elavil®, Luvox®, Pamelor®, Paxil®, Prozac®, or Zoloft® within the past 2 weeks.

When selegiline is taken at doses of 10 mg or less daily for the treating Parkinson's disease, there aren't any restrictions on food or beverages consume or drink. However, the chance exists that dangerous reactions, including sudden high blood pressure level, may occur if doses greater than those used for Parkinson's disease are taken with food items, beverages, or other medicines. These foods, beverages, and medicines include:

Also, for around two weeks as soon as you stop taking this medicine, these foods, beverages, along with other medicines may continue to react with selegiline whether or not this was taken in doses higher than those usually useful for Parkinson's disease.

Check with your doctor or hospital er immediately if severe headache, stiff neck, chest pains, fast heartbeat, or nausea and vomiting occur while you're taking this medicine. These may be symptoms of a serious side effect which will have a doctor's attention.

Dizziness, lightheadedness, or fainting may occur, especially when you receive up coming from a lying or sitting position. Getting up slowly could help. If the problem continues or gets worse, seek advice from your doctor.

Selegiline could potentially cause dryness with the mouth. For temporary relief, use sugarless candy or gum, melt components of ice with your mouth, or utilize a saliva substitute. However, if the mouth will continue to feel dry for over fourteen days, check with your medical doctor or dentist. Continuing dryness from the mouth may increase the chance of dental disease, including cavities, gum disease, and fungus infections.

It is very important that your doctor look at your skin for melanoma (tumor) regularly if you might have Parkinson's disease.

Do not stop using this medicine without first checking with your medical professional. Your doctor might want you to reduce gradually the amount you're taking before stopping completely.

Hallucinations may happen in some patients. This is more prevalent with elderly patients. If you might have hallucinations, consult your medical professional.

Some people who have used this medicine had unusual changes in their behavior. Talk with your doctor in case you start having problems with gambling or increased sexual drive while by using this medicine.

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