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Precautions

Do NOT use Clonidine if:

• you're allergic to the ingredient in Clonidine
• you happen to be pregnant, in labor, or going to begin labor
• you've bleeding problems
• you are taking an anticoagulant (eg, warfarin, heparin).

Contact your physician or health care provider right away if all of these sign up for you.

Some health conditions may talk with Clonidine. Tell your medical professional or pharmacist in case you have any medical ailments, particularly when any from the following affect you:

• if you are pregnant, likely to become pregnant, or are breast-feeding
• if you consider any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or another substances
• in case you have kidney problems, porphyria, or depression
• if you have circulation system disease affecting the mind or severe heart problems, or you might have had a stroke or possibly a recent heart attack
• if you are scheduled for surgery.

Some medicines may interact with Clonidine. Tell your medical provider if you are taking any other medicines, especially any in the following:

• Beta-blockers (eg, propranolol), calcium channel blockers (eg, verapamil), or digitalis because a severe reduction in pulse rate may occur
• Tricyclic antidepressants (eg, amitriptyline) as the effectiveness of Clonidine might be decreased and certain unwanted side effects could possibly be increased
• Anticoagulant therapy (eg, warfarin, heparin) since the chance of bleeding in the injection site could be increased.

This is probably not an entire set of all interactions that may occur. Ask your health care provider if Clonidine may communicate with other medicines that you take. Check with your medical provider before starting, stop, or affect the dose associated with a medicine.

Important safety information:

• Clonidine may cause drowsiness, dizziness, or lightheadedness. These effects may be worse if you get it with alcohol or certain medicines. Use Clonidine with caution. Do not drive or perform other possibly unsafe tasks unless you know how you react to it.
• Do not consume alcohol or use medicines that could potentially cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Clonidine; it may well increase their effects. Ask the pharmacist for those who have questions about which medicines may cause drowsiness.
• Clonidine might cause dizziness, lightheadedness, or fainting; alcohol, summer, exercise, or fever may increase these effects. To prevent them, crunch or stand slowly, especially in the morning. Sit or lay down on the first manifestation of all of these effects.
• Do not suddenly stop taking Clonidine. Doing so might cause withdrawal symptoms like nervousness, irritability, or shakiness. You could also get a headache and high blood pressure. The likelihood of these effects could possibly be greater when you have been taking high doses of Clonidine. The risk can also be greater if you take a beta-blocker (eg, atenolol). Rarely, serious effects like increased blood pressure inside brain, stroke, or death have occurred. Check with your physician when you alter your dose or stop Clonidine.
• If you go through dry mouth, use candy or gum, or melt pieces of ice with your mouth.
• Use Clonidine with caution in the elderly; they could be more sensitive to its effects, especially dizziness.
• Clonidine needs to be used with careful attention in youngsters; safety and effectiveness in children have not been confirmed. Use is tied to patients old enough to tolerate placement and treatments for an epidural catheter.
• Pregnancy and breast-feeding: If you get pregnant, contact your physician. You will need to discuss the rewards and perils of using Clonidine while you're pregnant. Clonidine is found in breast milk. If you might be or will likely be breast-feeding when you use Clonidine, seek advice from your doctor. Discuss any possible risks in your baby.

If you stop taking Clonidine suddenly, you might have withdrawal symptoms. These may include nervousness, agitation, headache, tremor, and rapid increase in hypertension.