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Precautions

Do NOT use Zoloft if:

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• you are allergic to the ingredient in Zoloft

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• you consider or took a monoamine oxidase inhibitor (MAOI) (eg, phenelzine), selegiline, or St. John's wort during the last 14 days

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• you take a fenfluramine derivative (eg, dexfenfluramine), an H₁ antagonist (eg, astemizole, terfenadine), nefazodone, pimozide, sibutramine, or thioridazine.

Contact your medical professional or health care provider immediately if any of these connect with you.

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Some health conditions may communicate with Zoloft. Tell your doctor or pharmacist for those who have any health concerns, especially if any of the following affect you:

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• if you are pregnant, about to get pregnant, or are breast-feeding

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• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

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• for those who have allergies to medicines, foods, or any other substances

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• if you or a member of the family carries a history of bipolar disorder (manic-depression), other mental or mood problems, suicidal thoughts or attempts, or alcohol or substance abuse

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• if you have a reputation seizures, heart related illnesses, liver problems, stomach or bowel bleeding, or metabolism problems

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• if you might be dehydrated, have low blood sodium levels, or consume alcohol
• if you'll be having electroconvulsive therapy (ECT).

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Some medicines may talk with Zoloft. Tell your medical provider if you are taking every other medicines, especially any of the following:

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• Anorexiants (eg, phentermine), fenfluramine derivatives (eg, dexfenfluramine), linezolid, MAOIs (eg, phenelzine), metoclopramide, nefazodone, selegiline, serotonin 5-HT₁ receptor agonists (eg, sumatriptan), sibutramine, St. John's wort, or trazodone because severe unwanted effects, for instance a reaction that may include fever, rigid muscles, blood pressure level changes, mental changes, confusion, irritability, agitation, delirium, and coma, may occur

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• Anticoagulants (eg, warfarin), aspirin, or nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen) for the reason that risk of bleeding, including stomach bleeding, could be increased

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• Diuretics (eg, furosemide, hydrochlorothiazide) as the risk of high or low blood sodium levels might be increased
• Tramadol as the probability of seizures might be increased
• H₁ antagonists (eg, astemizole, terfenadine) or phenothiazines (eg, chlorpromazine, thioridazine) because severe cardiovascular disease, including irregular heartbeat, may occur
• Carbamazepine or cyproheptadine because they may decrease Zoloft's effectiveness

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• Aripiprazole, clozapine, digoxin, flecainide, lithium, phenytoin, pimozide, propafenone, risperidone, tricyclic antidepressants (eg, amitriptyline), or valproate (eg, valproic acid) since the chance of their unwanted effects could possibly be increased by Zoloft.

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This is probably not a complete report on all interactions that will occur. Ask your medical provider if Zoloft may connect to other medicines that you just take. Check using your health care provider before starting, stop, or alter the dose associated with a medicine.

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Important safety information:

• Zoloft could potentially cause drowsiness or dizziness. These effects could be worse if you go with alcohol or certain medicines. Use Zoloft with caution. Do not drive or perform other possible unsafe tasks before you recognize how you respond to it.

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• Do not are drinking alcoholic beverages as you take Zoloft.

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• Check along with your doctor before you use medicines that might cause drowsiness (eg, sleep aids, muscle relaxers) whilst you consider Zoloft; it might enhance their effects. Ask your pharmacist when you have questions regarding which medicines could potentially cause drowsiness.

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• Several weeks may pass before your symptoms improve. Do NOT take a lot more than the recommended dose, alter your dose, or use Zoloft for over prescribed without checking along with your doctor.

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• Children and teenagers having Zoloft could possibly be at increased risk for suicidal thoughts or actions. Adults are often affected. The risk could possibly be greater in patients who've had suicidal thoughts or actions inside past. The risk may also be greater in patients who may have had bipolar (manic-depressive) illness, or if themselves members experienced it. Watch patients having Zoloft closely. Contact the physician at once if new, worsened, or sudden symptoms such as depressed mood; anxious, restless, or irritable behavior; anxiety attacks; or any unusual change in mood or behavior occur. Contact your physician straight away if any signs of suicidal thoughts or actions occur.

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• If your medical professional tells you to avoid taking Zoloft, you simply must wait for a few months before you begin to adopt certain other medicines (eg, MAOIs, nefazodone). Ask your doctor ought to start to look at your new medicines after you've got stopped taking Zoloft.

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• Zoloft may rarely create a prolonged, painful erection. This could happen even when you happen to be not having sex. If this is not treated immediately, it could cause permanent sexual difficulties including impotence. Contact your doctor immediately in such a circumstance.

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• Serotonin syndrome is a possibly fatal syndrome that could be a result of Zoloft. Your risk could be greater if you take Zoloft with certain other medicines (eg, "triptans," MAOIs). Symptoms can include agitation; confusion; hallucinations; coma; fever; fast or irregular heartbeat; tremor; sweating; and nausea, vomiting, or diarrhea. Contact your doctor simultaneously in case you have some of these symptoms.

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• Neuroleptic malignant syndrome (NMS) can be a possibly fatal syndrome that may be caused by Zoloft. Symptoms might include fever; stiff muscles; confusion; abnormal thinking; fast or irregular heartbeat; and sweating. Contact your doctor at the same time if you have all of these symptoms.

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• Caution is recommended when you use Zoloft inside the elderly; they might be more sensitive to its effects, especially low blood sodium levels.

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• Caution is advised when you use Zoloft in kids; they could possibly be more sensitive to its effects, especially increased probability of suicidal thoughts or actions.

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• Zoloft ought to be combined with warning in kids younger 6 years; safety and effectiveness of these children haven't been confirmed.

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• Pregnancy and breast-feeding: Zoloft could potentially cause injury to the fetus if it is employed over the last three months of childbearing. If you become pregnant, get hold of your doctor. You will need to discuss the advantages and perils of using Zoloft while you might be pregnant. It is not known if Zoloft can be found in breast milk. If you're or will be breast-feeding as you use Zoloft, check using your doctor. Discuss any possible risks in your baby.

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