This combination medication is employed to treat symptoms of Parkinson's disease or symptoms that are parkinson-likesuch as shakiness, stiffness, difficulty moving). Parkinson's disease is thought to be caused by too little of a substance that is naturally occurringdopamine) in the brain. Levodopa changes into dopamine in the mind, helping to control movement. Carbidopa stops the breakdown of levodopa in the bloodstream therefore more levodopa can enter the mind. Carbidopa can also reduce some of levodopa's part effects such as for instance nausea and vomiting.

How to use Sinemet

Take this medication by mouth with or without food as directed by the doctor, frequently 3 to 4 times each and every day.

Taking this medicine with food might help to decrease nausea. It is best to avoid a high-protein diet (it decreases the quantity of levodopa that the body takes in) during therapy, unless directed otherwise by your doctor. Separate your dosage with this medication by because hours that are many possible from any iron supplements or products containing iron (such as multivitamins with minerals) you may take. Iron can reduce the amount of this medication absorbed by the body. Consult your doctor or pharmacist to get more details.

The dosage is situated on your condition that is medical and to treatment. To reduce your risk of side effects, your doctor may direct you to start this medication at a dose that is low gradually increase your dose. Follow your doctor's guidelines carefully. This combination medication comes in different strengths with various amounts of carbidopa and levodopa in each tablet. Be sure you have the correct strength of both drugs. Your doctor might also alone prescribe carbidopa to be taken with this combination.

Make use of this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.

Some clients may experience a "wearing-off" (worsening of symptoms) prior to the next dose is due. An "on-off" impact may also occur, in which unexpected short periods of stiffness occur. If these effects occur, contact your medical professional for possible dose adjustments which could help to lessen this effect.

Do not stop taking this medication without consulting your physician. Some conditions can become worse whenever this drug is quickly reduced or suddenly stopped. Your dose may need to be gradually reduced. (See also negative effects part.)

Inform your physician when your condition will not enhance or if it worsens.

adverse Impacts

Dizziness, lightheadedness, nausea, vomiting, loss of appetite, difficulty sleeping, uncommon dreams, or headache may take place. If some of these effects persist or worsen, tell your pharmacist or doctor promptly.

This medication may cause saliva, urine, or sweat to turn a dark color. This effect is harmless, but your clothes could be stained.

To lessen the possibility of dizziness and lightheadedness, get fully up slowly when rising from a sitting or position that is lying.

Remember that your doctor has prescribed this medicine because he or she has judged that the benefit to you is greater than the risk of adverse effects. Many people using this medication do not have side that is serious.

Some individuals taking this medication have dropped asleep abruptly throughout their usual daily activities (such as talking on the phone, driving). In some full instances, sleep occurred without any emotions of drowsiness in advance. This sleep effect may occur anytime during treatment with carbidopa/levodopa even though you have used this medication for a long time. If you experience increased sleepiness or fall asleep during the day, do not drive or do other possibly dangerous activities until you have discussed this effect with your doctor. Your risk of the sleep impact is increased by using liquor or other medications that can allow you to drowsy. See also Precautions section.

Tell your physician immediately if you have any serious side effects, including: new/worsening movements you can't control/spasms, greatly increased eye blinking/twitching, fainting, vision changes (such as blurred vision, double vision), eye pain, severe stomach/abdominal pain, black/tarry stools, vomit that looks like coffee grounds, mental/mood changes (such as agitation, hallucinations, depression, thoughts of suicide), signs of infection (such as sore throat that doesn't go away), easy bleeding/bruising, unusual tiredness, tingling of the hands/feet, unusual strong urges (such as increased gambling, increased sexual urges).

Get help that is medical away if you have actually any very serious side results, including: chest pain.

Suddenly stopping or reducing the dose of the medicine may hardly ever cause an extremely condition that is serious neuroleptic malignant syndrome (NMS). Get medical help right away when you yourself have any of the following symptoms: fever, unusual muscle stiffness, severe confusion, sweating, fast/irregular heartbeat, fast breathing.

a very serious reaction that is allergic this drug is rare. However, get medical help right away in the event that you notice any outward symptoms of a critical allergic reaction, including: rash, itching/swelling (especially for the face/tongue/throat), severe dizziness, trouble respiration.

This is maybe not a list that is complete of side effects. If you notice other effects not listed above, contact your pharmacist or doctor.

In the usa -

Call your physician for medical advice about adverse effects. You could report adverse effects to FDA at 1-800-FDA-1088 or at

In Canada - Call your medical practitioner for medical advice about side effects. You may report effects that are side Health Canada at 1-866-234-2345.


Before using this medicine, tell your doctor or pharmacist if you are allergic to carbidopa or levodopa; or if you have any other allergies. This product may contain ingredients that are inactive which can cause allergy symptoms or other problems. Talk to your pharmacist for lots more details.

Before applying this medicine, tell your doctor or pharmacist your health background, especially of: liver disease, glaucoma, respiration problems (such as for instance asthma), heart disease (such as for instance heart attack, irregular heartbeat), kidney infection, stomach/intestinal ulcer, mental/mood disorders (such as for instance depression, schizophrenia), blood disorders, seizures, rest disorders.

This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness you can perform such activities safely until you are sure. Limit alcoholic beverages. See also Side Results section.

Before having surgery, tell your doctor or dentist about most of the products you utilize (including prescription drugs, nonprescription drugs, and organic products).

During pregnancy, this medication should be utilized only if obviously required. Discuss the potential risks and benefits with your physician.

Levodopa passes into breast milk. It's unknown if carbidopa passes into breast milk. Consult your medical practitioner before breast-feeding.

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