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Precautions

Do NOT use Plavix if:

• you're allergic to the ingredient in Plavix
• you offer an active bleeding disorder, such as a stomach ulcer or bleeding inside the brain
• you take certain azole antifungals (eg, fluconazole, ketoconazole, voriconazole), cimetidine, etravirine, felbamate, fluoxetine, fluvoxamine, certain proton pump inhibitors (eg, omeprazole, esomeprazole), or ticlopidine.

Contact your medical professional or health care provider immediately if all of these apply to you.

Some health conditions may connect to Plavix. Tell your physician or pharmacist if you have any medical conditions, particularly when any from the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you take any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• when you have allergies to medicines, foods, and other substances
• when you have bone marrow disease, liver or kidney problems, or perhaps a history of ulcers
• for those who have a recent injury or surgery, including dental surgery.

Some medicines may communicate with Plavix. Tell your health care provider if you consider some other medicines, especially any from the following:

• Dabigatran, nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), oral anticoagulants (eg, warfarin), or salicylates (eg, aspirin) for the reason that risk of bleeding could possibly be increased by Plavix
• Azole antifungals (eg, ketoconazole), cimetidine, etravirine, felbamate, fluoxetine, fluvoxamine, proton pump inhibitors (eg, omeprazole), or ticlopidine since they may decrease Plavix's effectiveness
• Fluvastatin, phenytoin, tamoxifen, tolbutamide, or torsemide because the chance of their unwanted effects could possibly be increased by Plavix.

This might not be a total set of all interactions that may occur. Ask your medical provider if Plavix may connect to other medicines that you take. Check with your health care provider prior to starting, stop, or change the dose of any medicine.

Important safety information:

• Plavix may cause dizziness. This effect could possibly be worse if you take it with alcohol or certain medicines. Use Plavix with caution. Do not drive or perform other possible unsafe tasks before you know how you react to it.
• Plavix may reduce the quantity of clot-forming cells (platelets) with your blood. Avoid activities that could cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your medical professional in case you have dark, tarry, or bloody stools.
• Tell your doctor or dentist that you simply take Plavix when you have any medical or dentistry, emergency care, or surgery. You may need to stop Plavix before you might have some types of surgery.
• Plavix should be converted within the body for it to be effective. This conversion does not occur too in some people (about 2% of white patients, 4% of black patients, and 14% of Chinese patients). The medicine may well not work as well over these patients. Your doctor may perform a test to evaluate how well your system can convert Plavix. Talk together with your doctor to find out more.
• Plavix mustn't be found in children; safety and effectiveness in youngsters are not confirmed.
• Pregnancy and breast-feeding: If you think you could possibly be pregnant, get hold of your doctor. You will need to discuss the huge benefits and risks of using Plavix while you happen to be pregnant. It is not known if Plavix is found in breast milk. Do not breastfeed while taking Plavix.