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Precautions

Do NOT use Plavix if:

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• you happen to be allergic to any ingredient in Plavix

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• you come with an active bleeding disorder, say for example a stomach ulcer or bleeding within the brain

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• you take certain azole antifungals (eg, fluconazole, ketoconazole, voriconazole), cimetidine, etravirine, felbamate, fluoxetine, fluvoxamine, certain proton pump inhibitors (eg, omeprazole, esomeprazole), or ticlopidine.

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Contact your doctor or physician immediately if all of these affect you.

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Some medical conditions may communicate with Plavix. Tell your medical professional or pharmacist if you have any medical ailments, especially if any of the following connect with you:

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• if you are pregnant, about to get pregnant, or are breast-feeding

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• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

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• when you have allergies to medicines, foods, or another substances

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• when you have bone marrow disease, liver or kidney problems, or a reputation ulcers

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• for those who have had a recent injury or surgery, including dental surgery.

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Some medicines may interact with Plavix. Tell your doctor if you consider some other medicines, especially any with the following:

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• Dabigatran, nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), oral anticoagulants (eg, warfarin), or salicylates (eg, aspirin) because the risk of bleeding could be increased by Plavix

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• Azole antifungals (eg, ketoconazole), cimetidine, etravirine, felbamate, fluoxetine, fluvoxamine, proton pump inhibitors (eg, omeprazole), or ticlopidine given that they may decrease Plavix's effectiveness

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• Fluvastatin, phenytoin, tamoxifen, tolbutamide, or torsemide as the likelihood of their unwanted effects might be increased by Plavix.

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This is probably not a whole report on all interactions which could occur. Ask your health care provider if Plavix may communicate with other medicines that you simply take. Check with your medical provider before you start, stop, or affect the dose of any medicine.

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Important safety information:

• Plavix could cause dizziness. This effect might be worse if you get it with alcohol or certain medicines. Use Plavix with caution. Do not drive or perform other possible unsafe tasks and soon you know how you reply to it.

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• Plavix may lessen the variety of clot-forming cells (platelets) within your blood. Avoid activities that may cause bruising or injury. Tell your medical professional for those who have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.

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• Tell your doctor or dentist that you take Plavix prior to deciding to have any medical or dental care, emergency care, or surgery. You may need to stop Plavix before you have certain kinds of surgery.

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• Plavix have to be converted within the body correctly to work. This conversion doesn't happen as well in most people (about 2% of white patients, 4% of black patients, and 14% of Chinese patients). The medicine might not exactly work at the same time over these patients. Your doctor may perform a test to check on how well your system is able to convert Plavix. Talk with your doctor to learn more.

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• Plavix shouldn't be utilized in children; safety and effectiveness in children haven't been confirmed.

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• Pregnancy and breast-feeding: If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and perils associated with using Plavix while you are pregnant. It is not known if Plavix is located in breast milk. Do not breastfeed while taking Plavix.

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