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Uses

INDICATIONS

Micronase (Glyburide) is definitely an oral diabetes medicine that helps control blood glucose levels.

Glyburide is utilized to deal with diabetes.

This medicine is not for treating type 1 diabetes.

Glyburide may also be used for other purposes unlisted in this medication guide.

INSTRUCTIONS

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Take just as prescribed because of your doctor. Do not take in larger or smaller amounts and more than recommended. Follow the directions on your prescription label. Your doctor may occasionally change your dose to make sure you receive the best results.

Take glyburide together with your first meal through the day, unless your medical professional informs you otherwise.

Your blood glucose levels should be checked often, and you will need other blood tests at your physician's office. Visit a medical expert regularly.
Know the indications of low blood glucose (hypoglycemia) and how to recognize them: headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating.

Always keep a source of sugar for sale in case you've signs of low blood glucose. Sugar sources include orange juice, glucose gel, candy, or milk. If you've severe hypoglycemia and should not eat or drink, use an injection of glucagon. Your doctor can provide you with a prescription for the glucagon emergency injection kit and show you the best way to give the injection.

Also look for signs of blood sugar that's too high (hyperglycemia). These symptoms include increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dermititis, blurred vision, and weight-loss.

Check your blood sugar levels carefully throughout a time of stress or illness, in the event you travel, exercise more than usual, consume alcohol, or skip meals. These things may affect your glucose levels along with your dose needs can also change.

Your doctor may wish that you stop taking glyburide for the small amount of time if you get sick, use a fever or infection, or if you have surgical treatment or a medical emergency.
Ask a medical expert the way to adjust your glyburide dose as needed. Do not change your medication dose or schedule without your doctor's advice.

If you will find any changes in the manufacturer, strength, or kind of glyburide you use, your dosage needs may change. Always check your refills to ensure that you have received the proper brand name and sort of medicine prescribed through your doctor.

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DOSAGE

Take as prescribed by your doctor.

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STORAGE

Store at room temperature, shielded from moisture, heat, and light-weight.

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MORE INFO:

Active ingredient: Glyburide

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Side Effects

Stop using glyburide and obtain emergency medical help if you've got any of these indications of a hypersensitive reaction: hives; lack of breath; swelling of your face, lips, tongue, or throat. Stop taking medicines and call your doctor immediately if you've got any of these serious unwanted side effects:

nausea, stomach pain, low fever, lack of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

pale skin, confusion or weakness;

easy bruising or bleeding, purple or red pinpoint spots beneath your skin; or

headache, trouble concentrating, memory problems, feeling unsteady, hallucinations, fainting, seizure, shallow breathing or breathing that stops.

Less serious negative effects may include:

mild nausea, heartburn, feeling full;

joint or muscle pain;

blurred vision; or

mild itching or skin rash.

This is not a complete list of negative effects yet others may occur. Call a medical expert for medical health advice about unwanted effects.

Precautions

You should avoid using prescription drugs in case you are allergic to glyburide, or:

if you are being treated with bosentan (Tracleer);

if you might have type 1 diabetes; or

if you are in a state of diabetic ketoacidosis (call your physician for treatment with insulin).

To be sure you can safely take glyburide, tell your doctor if you have these other difficulties:

hemolytic anemia (a lack of red blood cells);

an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD);

a nerve disorder affecting bodily functions;

liver or kidney disease;

should you are allergic to sulfa drugs; or

if you've got been using insulin or taking chlorpropamide (Diabinese).

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Certain oral diabetes medications may increase your likelihood of serious heart disease. However, not treating your diabetes can damage your heart along with other organs. Talk to your physician in regards to the risks and great things about handling your diabetes with glyburide.

FDA pregnancy category C. It is not known whether glyburide will harm an baby. Similar diabetes medications have caused severe hypoglycemia in babies whose mothers had used the medication at the duration of delivery. Tell your physician in the event you are pregnant or prefer to conceive while using medicines. It is not known whether glyburide passes into breast milk or if it could harm a nursing baby.

Do not use prescription drugs without telling your physician if you are breast-feeding your baby. Older adults might be prone to have low blood glucose while taking glyburide.

 

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Important safety information:

You should not use medicines in the event you are allergic to glyburide, if you are receiving care with bosentan (Tracleer), if you've got type 1 diabetes, or should you are in a state of diabetic ketoacidosis (call your medical professional for treatment with insulin).

Before taking glyburide, tell your medical professional should you are allergic to sulfa drugs, if you've got been using insulin or chlorpropamide (Diabinese), or if you have hemolytic anemia (too little red blood cells), an enzyme deficiency (G6PD), a nerve disorder, liver disease, or kidney disease.

Take care to not let your blood glucose get too low. Low blood glucose (hypoglycemia) can happen should you skip meals, exercise to much time, are drinking alcohol, or are under stress. Symptoms include headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating. Carry hard candy or glucose tablets together with you in case you've got low blood sugar levels. Other sugar sources include orange juice and milk. Be sure all your family members and pals know how you can help you in an emergency.

Drug interactions

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Tell your doctor about other medications you have, especially:

a blood thinner like warfarin (Coumadin, Jantoven);

cyclosporine (Gengraf, Neoral, Sandimmune);

disopyramide (Norpace);

fluconazole (Diflucan), ketoconazole (Nizoral);

fluoxetine (Prozac);

rifampin (Rifadin, Rimactane, Rifater);

an ACE inhibitor like enalapril (Vasotec), lisinopril (Prinivil, Zestril), ramipril (Altace), yet others; or

an antibiotic like ciprofloxacin (Cipro), levofloxacin (Levaquin), while others.

Using certain medicines makes it more difficult for you to definitely tell when you have low blood glucose. Tell your doctor should you use these things:

albuterol (Proventil, Ventolin);

clonidine (Catapres);

reserpine; or

beta-blockers like atenolol (Tenormin), carvedilol (Coreg), metoprolol (Lopressor, Toprol), propranolol (Inderal, InnoPran), while others.

You could possibly be more prone to have hyperglycemia (high blood glucose levels) in case you take glyburide with:

isoniazid;

diuretics (water pills);

steroids (prednisone among others);

phenothiazines (Compazine while others);

thyroid medicine (Synthroid among others);

birth control pills as well as other hormones;

heart or blood pressure level medications (Cartia, Cardizem, Nifedical, Covera, Verelan, and others);

niacin (Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, yet others);

seizure medicines (Dilantin and others); and

diet pills or medicines to help remedy asthma, colds or allergies.

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You may be more prone to have hypoglycemia (low blood sugar levels) should you take glyburide with:

clarithromycin (Biaxin);

exenatide (Byetta);

probenecid (Benemid);

heart or blood pressure medication (Accupril, Altace, Lotensin, Prinivil, Vasotec, Zestril, among others);

some nonsteroidal anti-inflammatory drugs (NSAIDs);

aspirin or any other salicylates (including Pepto-Bismol);

sulfa drugs (Bactrim, Gantanol, Septra, among others);

a monoamine oxidase inhibitor (MAOI); and

other oral diabetes medications, especially acarbose (Precose), metformin (Glucophage), miglitol (Glyset), pioglitazone (Actos), or rosiglitazone (Avandia).

These lists are certainly not complete and you can find many other medicines that will increase or say goodbye of glyburide on lowering your blood glucose levels. Tell a medical expert about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not take up a new medication without telling your doctor.

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