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Uses

INDICATIONS

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Meldonium treats heart ischemia and its particular consequencesis.  It is employed in the management of brain circulation disorders. Meldonium is assumed to improve Mental Processes (Memory, Learning, Focus, Concentration, Processing of Information) and reduces Fatigue, Increases Motivation & Alertness. Meldonium was designed to enhance Athletic Training & Competitive Performance as well as microcirculation & Oxygen Delivery.

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Due to its unique mechanism of action Mildronate, with regards to the prescribed dose, is popular for treating different heart and vascular diseases, also as for that improvement of work capacity of healthy people at physical and mental overloads and during rehabilitation period.

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INSTRUCTIONS

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Applied internally.

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• Intellectual and physical stress (including in athletes). Adults – 1 g each day
divided into two 500mg doses. Course of treatment is 10-14 days. If necessary, the treatment is repeated in 2-3 weeks.

• Athletes should take 500 mg – 1 g twice a day before training. Duration of
treatment during preparatory period is 2-3 weeks, during the period of competition – 10-14 days.

• Cardiovascular disease. As part of combined therapy: 500 mg -1 g (1-2 tablets) each day, using the whole dose previously or dividing for just two takings. Course of treatment is 4-6 weeks.

• Cardialgia against the background of dyshormonal myocardiodystrophy – 500 mg per day. Course of treatment is 12 days.

• Disturbed cerebral circulation. In course of treatment after elimination of acute disorders: 500 mg – 1 g each day, taking the whole dose in the past or dividing it for two takings. In case of chronic disorders: 500 mg each day. General treatment is 4-6 weeks. Recurrent courses (usually 2-3 times a year) could possibly be taken after consulting a health care provider.

• Diseases of peripheral arteries. 500 mg two times a day.

• Abstinence syndrome in the event of chronic alcoholism. 500 mg 4x every day. Course of treatment is 7-10 days.

• Maximum daily dose is 2000 mg.

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Please consult your physician prior to by using this or other natural supplements or medications.

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DOSAGE

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Please consult your doctor regarding the required dosage.

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Overdosage
There isn't any data of cases of Meldonium overdosage. The drug is low-toxic.

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STORAGE 

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Keep far from sunlight.
Keep locked and from children.
Store in dry place at room temperature.
Do not exceed storage temperature above 25 C

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Side Effects

Rarely - allergy symptoms (redness, rash, itching, oedema), also as dyspepsia, tachycardia, excitement, changes of arterial pressure.

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Precautions

Contraindications:

Hypersensitivity, increased intracranial pressure (in violation with the venous outflow, intracranial tumors).

Restrictions:

Pregnancy, lactation, children under 18 (capsule, injectable solution) or 12 years (syrup), since safety and efficacy haven't been determined.

Pregnancy and breast-feeding:

Not recommended in pregnancy (safety weren't proven). At the time of treatment should stop breastfeeding (known perhaps the breast milk gets).

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Interaction to drugs and also other varieties of interaction

The drug may be along with antianginal agents, anticoagulants and antiaggregants, antiarrhythmic drugs, diuretics, and bronchial spasmolytics. It intensifies the action of coronary vasodilating drugs, some hypotensive agents, and cardiac glycosides. Taking into consideration the possible progression of mild tachycardia and arterial hypotension, care needs to be taken when combining the drug with nitroglycerin, nifediphine, alpha-adrenoceptor blockers, hypotensive agents and peripheral vasodilators.

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