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Keppra is used to deal with partial onset seizures in grown-ups and children who are a minimum of 1 month old.
It can also be used to deal with tonic-clonic seizures in older adults and youngsters who will be at least 6 years old, and myoclonic seizures in older adults and children who're no less than 12 yrs . old.
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Take Keppra exactly as prescribed by your doctor. Do not take in larger or smaller amounts or more than recommended. Follow the directions on your own prescription label.
Your doctor may occasionally improve your dose to ensure that you get the best results.
Keppra is generally taken twice every day. Take the medicine concurrently every day. You may take Keppra with or without food.
Measure liquid medicine with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask the pharmacist for one.
Do not crush, chew, or break a controlled release, delayed-release, or extended-release tablet. Swallow it whole. Breaking the pill could cause a lot of drug to be released previously.
Use Keppra regularly to have the most benefit. Get your prescription refilled before you run out of medication completely.
Do not stop using Keppra without first speaking with your doctor, in case you feel awesome. You might have increased seizures in the event you stop applying this medicine suddenly. You might need to use much less prior to deciding to stop the medication completely.
Seizures will often be treated with a combination of different drugs. Use all medications as directed from your doctor. Read the medication guide or patient instructions furnished with each medication. Do not change your doses or medication schedule without your medical professional's advice. .
Wear a medical alert tag or carry an ID card proclaiming that you are taking Keppra. Any medical treatment provider who treats you have to know that you're taking seizure medication.
To be certain Keppra isn't causing harmful effects, your kidney function ought to be tested. Visit your doctor regularly.
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If you missed a dose - go ahead and take missed dose when you remember. Skip the missed dose whether it is almost time for your upcoming scheduled dose. Do not take extra medicine to produce in the missed dose.
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Important Administration Instructions
Keppra is given orally with or without food. The Keppra dosing regimen depends on the indication, age bracket, dosage form (tablets or oral solution), and renal function.
Prescribe the oral solution for pediatric patients with body weight ≤ 20 kg. Prescribe the oral solution or tablets for pediatric patients with bodyweight above 20 kg.
When while using oral solution in pediatric patients, dosing is weight-based (mg per kg) by using a calibrated measuring device (not only a household teaspoon or tablespoon).
Keppra tablets must be swallowed whole. Keppra tablets should not be chewed or crushed.
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Treatment should be initiated using a daily dose of 14 mg/kg by 50 % divided doses (7 mg/kg twice daily). The daily dose should be increased every 2 weeks by increments of 14 mg/kg to the recommended daily dose of 42 mg/kg (21 mg/kg twice daily). In the clinical study, the mean daily dose was 35 mg/kg on this population. The effectiveness of lower doses is not studied.
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Treatment ought to be initiated having a daily dose of 20 mg/kg by 50 % divided doses (10 mg/kg twice a day). The daily dose should be increased by 50 % weeks by an increment of 20 mg/kg on the recommended daily dose of 50 mg/kg (25 mg/kg two tmes a day). If a patient cannot tolerate a day-to-day dose of 50 mg/kg, the daily dose could be reduced. In the clinical trial, the mean daily dose was 47 mg/kg within this generation.
Treatment must be initiated with a daily dose of 20 mg/kg into two divided doses (10 mg/kg twice a day). The daily dose should be increased every two weeks by increments of 20 mg/kg for the recommended daily dose of 60 mg/kg (30 mg/kg twice a day). If a patient cannot tolerate a regular dose of 60 mg/kg, the daily dose might be reduced. In the clinical efficacy trial, the mean daily dose was 44 mg/kg. The maximum daily dose was 3000 mg/day.
For Keppra tablet dosing in pediatric patients weighing 20 to 40 kg, treatment must be initiated which has a daily dose of 500 mg given as twice a day dosing (250 mg two tmes a day). The daily dose ought to be increased every 14 days by increments of 500 mg with a maximum recommended daily dose of 1500 mg (750 mg twice daily).
For Keppra tablet dosing in pediatric patients weighing more than 40 kg, treatment ought to be initiated which has a daily dose of 1000 mg/day given as twice a day dosing (500 mg twice daily). The daily dose ought to be increased every fourteen days by increments of 1000 mg/day to some maximum recommended daily dose of 3000 mg (1500 mg twice daily).
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Partial Onset Seizures
Adults 16 Years And Older
In many studies, daily doses of 1000 mg, 2000 mg, and 3000 mg, given as twice-daily dosing were shown to be effective. Although in certain studies there was clearly an inclination toward greater response with higher dose [see Clinical Studies], a consistent rise in response with increased dose will not be shown.
Treatment ought to be initiated using a daily dose of 1000 mg/day, given as twice-daily dosing (500 mg two times a day). Additional dosing increments may be given (1000 mg/day additional every 14 days) with a maximum recommended daily dose of 3000 mg. Doses greater than 3000 mg/day are actually employed in open-label studies for periods of half a year and longer. There is no evidence that doses more than 3000 mg/day confer additional benefit.
Myoclonic Seizures In Patients 12 Years of Age and Older With Juvenile Myoclonic Epilepsy
Treatment must be initiated using a dose of 1000 mg/day, given as twice-daily dosing (500 mg two times a day). Dosage ought to be increased by 1000 mg/day every 14 days to the recommended daily dose of 3000 mg. The effectiveness of doses lower than 3000 mg/day will not be studied.
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Primary Generalized Tonic-Clonic Seizures
Adults 16 Years And Older
Treatment ought to be initiated with a dose of 1000 mg/day, given as twice-daily dosing (500 mg twice a day). Dosage needs to be increased by 1000 mg/day every fourteen days towards the recommended daily dose of 3000 mg. The effectiveness of doses under 3000 mg/day hasn't been adequately studied.
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Pediatric Patients Ages 6 To < 16 Years
Treatment should be initiated which has a daily dose of 20 mg/kg by 50 percent divided doses (10 mg/kg two tmes a day). The daily dose ought to be increased every two weeks by increments of 20 mg/kg towards the recommended daily dose of 60 mg/kg (30 mg/kg twice daily). The effectiveness of doses under 60 mg/kg/day will not be adequately studied. Patients with body mass ≤ 20 kg should be dosed with oral solution. Patients with bodyweight above 20 kg may be dosed with either tablets or oral solution. Only whole tablets should be administered.
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Adult Patients With Impaired Renal Function
Keppra dosing should be individualized according to the patient's renal function status.
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Store Keppra at room temperature away from moisture, heat, and lightweight.
Get emergency medical help if you have some of these warning signs of an allergic reaction to Keppra: hives; difficult breathing; swelling of one's face, lips, tongue, or throat.
Report any new or worsening symptoms to your doctor, including: mood or behavior changes, depression, anxiety, or in case you feel agitated, hostile, irritable, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.
Call a medical expert simultaneously in case you use a serious complication for example:
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Less serious Keppra unwanted effects may include:
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This is just not a complete listing of unwanted side effects while others may occur. Tell your doctor about any unusual or bothersome complication.
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You must avoid using Keppra in case you are allergic to levetiracetam.
To ensure you can safely take Keppra, tell your doctor if you have kidney disease or high blood pressure levels.
You could possibly have thoughts about suicide while investing in this medicine. Tell your medical professional in case you have the signs of depression or suicidal thoughts through the first several weeks of treatment, or whenever your dose is changed.
Your family or any other caregivers should also be tuned in to changes inside your mood or symptoms. Your doctor should check you at regular visits.
FDA pregnancy category C. It is not known whether Keppra will harm an child, but having a seizure during pregnancy could harm both the mother along with the baby. Tell your physician in the event you are pregnant or want to conceive while using this medication. Do not start or stop taking Keppra during pregnancy without your doctor's advice. Seizure control is very important while pregnant. The benefit of preventing seizures may outweigh any risks posed by taking Keppra. Follow a medical expert's instructions about taking Keppra while you're pregnant. Levetiracetam can pass into breast milk and may even harm a nursing baby. You should not breast-feed if you are using Keppra. Do not give prescription drugs to some child devoid of the advice of the doctor. Your child's dose needs are based on age and weight. The child should remain underneath the care of an doctor while employing this medicine.
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Do not stop using Keppra without first talking to your physician, in case you feel fine. You may have increased seizures if you stop using Keppra suddenly. You should use less and less before you decide to stop the medication completely.
You could have thoughts about suicide while taking Keppra. Your doctor will likely need to check you at regular visits. Do not miss any scheduled appointments.
Report any new or worsening symptoms to a medical expert, like: mood or behavior changes, depression, anxiety, or should you feel agitated, hostile, irritable, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.
Wear a medical alert tag or carry an ID card on the grounds that you are taking Keppra. Any medical treatment provider who treats you have to know that you adopt seizure medication.
Keppra may impair your opinions or reactions. Be careful if you drive or a single thing that requires one to be alert. Tell a medical expert should you are pregnant or want to get pregnant while using this medication. Do not start or stop taking Keppra when pregnant without a medical expert's advice. Having a seizure in pregnancy could harm the two mother and also the baby. Seizure control is vital during pregnancy as well as the important things about preventing seizures may outweigh any risks posed by using Keppra.
Avoid having a drink. It can increase a few of the side effects of Keppra and might may also increase potential risk of seizures. This medication may impair your notions or reactions. Be careful if you drive or do just about anything that needs you to definitely be alert.
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