This medicine is used to treat movement problems due to Parkinson's disease. It does not cure Parkinson's disease, however it may enhance shakiness (tremor), muscle stiffness, loss of normal movement as your dose of other Parkinson's medication wears down (end-of-dose failure), and sudden switching between normal movement and stiffness ("on-off" problems). It may improve your range of motion and ability to walk, dress, and exercise. Selegiline is frequently used in combination with other medicines (e.g., levodopa, carbidopa).
Selegiline is an enzyme blocker (MAO inhibitor) that actually works by slowing the break down of specific natural substances in the brain (neurotransmitters such as for example dopamine, norepinephrine, and serotonin).
Take this medication by mouth, frequently twice daily with breakfast and lunch. Taking selegiline late in the day may cause trouble sleeping. Dosage is based on your medical condition and response to therapy. Do not increase your dose or often take it more than directed.
After you have been taking selegiline for 2 or 3 days, your doctor may direct you to lower your levodopa dose. Follow your doctor's instructions closely. Don't stop or alter the dose of any of your medications without first talking together with your doctor.
It might take a few weeks for the complete advantages of the drug to be noticed. Don't stop taking this drug without first consulting your doctor. Talk to your medical practitioner if the medication stops working well or if your trouble worsens.
Dizziness, abdominal pain, dry mouth, nausea, stomach upset, difficulty sleeping, and headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist quickly.
You may experience more adverse effects from the levodopa when taking selegiline if you are also taking levodopa. Tell your doctor right away if any of these adverse effects occur: nausea, shakiness, muscle stiffness, mental/mood changes such as hallucinations/abnormal dreams. Your doctor may need to change your dose or medication. Do not stop or change the dose of your levodopa without talking with your physician first.
Understand that your medical practitioner has recommended this medicine because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious adverse effects.
Some individuals taking selegiline have fallen asleep suddenly during their usual daily activities (such as talking on the phone, driving). In some full cases, sleep happened without any feelings of drowsiness beforehand. This sleep effect may occur anytime during therapy with selegiline even although you have used this medication for a time that is long. If you experience increased sleepiness or fall asleep during the day, do not drive or take part in other possibly dangerous activities until you have discussed this effect with your doctor. Your threat of this sleep effect is increased by utilizing liquor or other medications that can prompt you to drowsy. See also Precautions part.
Tell your physician appropriate away if you have any serious side effects, including: fainting, loss of balance, mental/mood changes (age.g., agitation, confusion, depression, hallucinations), unusual strong urges (such as increased gambling, increased intimate urges), worsening muscle stiffness/twitching, changes in sexual ability/interest, increased shaking (tremor), distended ankles/legs, difficulty urinating, uncommon weight gain, effortless bleeding/bruising, black/tarry stools, vomit that looks like coffee grounds.
This drug may rarely cause an assault of extremely blood that is high (hypertensive crisis), which may be fatal. Many drug and food interactions can increase this danger. (See also Drug Interactions section.) Get medical help right away if some of these serious unwanted effects occur: frequent/severe headache, fast/slow/irregular/pounding heartbeat, chest discomfort, neck stiffness/soreness, serious nausea/vomiting, sweating/clammy skin (sometimes with fever), widened pupils, vision changes (e.g., double/blurred eyesight), sudden sensitivity to light (photophobia).
This medication may increase serotonin and rarely cause a very condition that is serious serotonin syndrome. The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take. Get medical help right away in the event that you develop some associated with after signs: hallucinations, unusual restlessness, loss in coordination, fast heartbeat, severe dizziness, unexplained fever, severe nausea/vomiting/diarrhea, twitching muscle.
A really severe allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic attack, including: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble respiration.
This isn't a list that is complete of side effects. If you notice other effects not listed above, contact your pharmacist or doctor.
In the US -
Call your physician for medical advice about side-effects. You may report side effects to Food And Drug Administration at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about side effects. You may report adverse effects to wellness Canada at 1-866-234-2345.
Before taking selegiline, tell your physician or pharmacist if you have any other allergies if you are allergic to it; or. This product may contain inactive ingredients, which could cause allergic reactions or other problems. Speak to your pharmacist for more details.
Before using this medication, tell your medical professional or pharmacist your medical history, particularly of: a particular sort of adrenal gland tumefaction (pheochromocytoma), cerebrovascular infection (age.g., stroke), heart disease (e.g., congestive heart failure, coronary attack), bleeding problems, history of severe/frequent headaches, peptic ulcer, diabetes, personal/family history of mental/mood disorders (age.g., schizophrenia, bipolar disorder), personal/family reputation for high blood pressure, liver illness, overactive thyroid (hyperthyroidism).
This drug might make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness you can perform such activities safely until you are sure. Limit alcoholic beverages. See also Part Effects section.
To minimize dizziness plus the danger of fainting, get right up slowly when rising from a sitting or position that is lying.
Before having surgery, tell your dentist or doctor you are taking this medication. You may need certainly to stop using this medication beforehand. Follow your doctor's instructions carefully.
Selegiline is used only once obviously required during pregnancy. Discuss the potential risks and benefits with your doctor.
It's not known if this drug passes into breast milk. Consult your medical practitioner before breast-feeding.
Airmail: 2-3 business weeks, EMS: 3-8 business days.
Airmail: 2-3 business weeks, EMS: 3-8 business days.