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Detrol is indicated for your management of overactive bladder with signs of urge urinary incontinence, urgency, and frequency.

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INSTRUCTIONS

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Take Detrol just as prescribed from your doctor. Do not take in larger or smaller amounts and for over recommended. Follow the directions on your own prescription label.

Your doctor may occasionally improve your dose to ensure that you obtain the best results.

Take Detrol with water. Do not crush, chew, break, or open a controlled-release capsule. Swallow it whole. Breaking or opening the pill could cause excessive drug to be removed in the past.

Store Detrol at room temperature away from moisture and heat.

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If you missed a dose - go ahead and take missed dose when you remember. Skip the missed dose when it is almost time for your next scheduled dose. Do not take extra medicine to create in the missed dose.

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DOSAGE

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The recommended dose of Detrol Capsules is 4 mg once daily with water and swallowed whole. The dose could be lowered to 2 mg daily based on individual response and tolerability; however, limited efficacy data are around for Detrol 2 mg.

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For patients with mild to moderate hepatic impairment (Child-Pugh Class A or B) or severe renal impairment (CCr 10-30 mL/min), the recommended dose of Detrol is 2 mg once daily. Detrol is not recommended for utilization in patients with severe hepatic impairment (Child-Pugh Class C). Patients with CCKlO mL/min have not been studied and employ of Detrol on this population is not recommended.

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For patients who will be taking drugs which are potent inhibitors of CYP3A4 [e.g., ketoconazole, clarithromycin, ritonavir], the recommended dose of Detrol is 2 mg once daily.

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STORAGE

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Store Detrol at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store far from heat, moisture, and light. Do not store within the bathroom. Keep Detrol out of your reach of children and away from pets.

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Side Effects

Get emergency medical help in case you have some of these signs of a hypersensitive reaction to Detrol: hives; lack of breath; swelling of your face, lips, tongue, or throat. Stop using Detrol and call your physician at once if you have these serious unwanted effects:

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Less serious Detrol side effects can sometimes include:

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This isn't a complete report on unwanted effects while others may occur. Call a medical expert for medical advice about unwanted effects.

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Precautions

Before taking tolterodine, tell your medical professional or pharmacist if you're allergic for it; or when you have every other allergies. This product may contain inactive ingredients, that may cause allergy symptoms or any other problems. Talk to your pharmacist for more information.

This medication shouldn't be used when you have certain medical conditions. Before using this medicine, consult your physician or pharmacist for those who have: problems emptying your bladder (urinary retention), severe blockage of stomach/intestines (gastric retention), some eye condition (uncontrolled narrow-angle glaucoma).

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Before employing this medication, tell a medical expert or pharmacist your history, especially of: other bladder problems (e.g., bladder outflow obstruction), stomach/intestinal disease (e.g., ulcerative colitis), slowed movement of stomach/intestines, severe constipation, controlled narrow-angle glaucoma, kidney disease, liver disease, enlarged prostate, a specific muscle disease (myasthenia gravis).

Tolterodine may cause a complaint that affects the heart rhythm (QT prolongation). QT prolongation can infrequently cause serious (rarely fatal) fast/irregular heartbeat as well as other symptoms (such as severe dizziness, fainting) that want immediate medical help. The likelihood of QT prolongation may be increased in case you have certain health conditions or take other drugs that will affect one's heart rhythm (see also Drug Interactions section). Before using tolterodine, tell your doctor or pharmacist when you have any of these conditions: certain cardiovascular disease (heart failure, slow heartbeat, QT prolongation inside the EKG), family history of certain heart problems (QT prolongation inside EKG, sudden cardiac death).

Low levels of potassium or magnesium inside the blood could also increase your probability of QT prolongation. This risk may increase the use of certain drugs (including diuretics/"water pills") or in case you have conditions like severe sweating, diarrhea, or vomiting. Talk to your doctor about using tolterodine safely.

This drug will make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or go activity that will require alertness or clear vision unless you are sure it is possible to perform such activities safely. Limit booze.

This medication might cause decreased sweating. Avoid becoming overheated in summer, saunas, or during exercise and other strenuous activities since heatstroke may occur.

Kidney function declines while you age group. This medication is taken away from the kidneys. Therefore, seniors could be more responsive to this drug.

This medication should be used only if clearly needed while pregnant. It is not known whether Detrol will harm an child. Tell your doctor in case you are pregnant or prefer to get pregnant while employing this medication. Discuss the risks and benefits with a medical expert.

It is unknown if the drug passes into breast milk. Consult your doctor before breast-feeding.

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