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Precautions

Do NOT use Coumadin if:

• you are allergic to your ingredient in Coumadin
• you have bleeding tendencies, bleeding problems (eg, hemophilia), severe or uncontrolled hypertension, certain blood problems (eg, low white blood cell or platelet levels), or leukemia
• you've active serious bleeding, bleeding within the brain, certain circulation system problems (eg, aneurysm, dissecting aorta), or inflammation or infection of the heart
• you have active ulcer or bleeding in the stomach or bowel, urinary tract, genitals, or respiratory tract
• you have recently had or is going to be having eye, brain, or spinal-cord surgery; spinal puncture; spinal anesthesia; or any form of major surgery
• you are pregnant or can become pregnant
• you are unable to have routine blood clotting tests
• you are unable to follow a medical expert's instructions properly and never have someone that will help you take your medicine
• you consider mifepristone, streptokinase, or urokinase.

Contact your doctor or health care provider straight away if these connect with you.

Some health concerns may interact with Coumadin. Tell a medical expert or pharmacist when you have any medical conditions, particularly when any from the following connect with you:

• if you are planning to conceive or are breast-feeding
• in case you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• for those who have allergies to medicines or other substances
• in case you have ended up injured, fallen, given birth, or had surgery
• in case you have a good reputation for stomach or bowel problems (eg, bleeding, ulcer, inflammation), cardiovascular disease (eg, heart failure, infection), blood clots, anemia and other blood problems (eg, protein C deficiency, high red blood cell levels), circulation system problems, or hypertension
• in case you have a good liver, kidney, or an under active thyroid; yellowing from the skin or eyes; mental or mood problems; high cholesterol levels; arthritis; diabetes; or cancer
• in case you have poor nutrition, celiac disease, nutrient or fat absorption problems, or 'abnormal' amounts of vitamin K or vitamin C within the blood, or in the event you drink alcohol
• in case you have a fever, inadequate health, diarrhea, fluid buildup, excessive fat in the stools (steatorrhea), a recently available or current infection, or tuberculosis, or in the event you will probably be encountered with high temperatures to get a prolonged duration of time
• when you have a heart valve replacement, an intrauterine device (IUD), or perhaps a catheter.

Some medicines may interact with Coumadin. Tell your medical provider in the event you take another medicines, especially any of the following:

• Heparin and other anticoagulants, nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), salicylates (eg, aspirin), streptokinase, or urokinase since the likelihood of bleeding could possibly be increased
• Mifepristone because excessive bleeding may occur
• Many prescription and nonprescription medicines (eg, useful for infections, inflammation, discomfort, blood pressure, high-cholesterol, seizures, mental or mood problems, diabetes, stomach or irregularity, irregular heartbeat, birth control, hormone replacement, cancer, and others), multivitamin products, and herbal or nutritional supplements (eg, herb teas, coenzyme Q10, garlic, ginseng, ginkgo, St. John's wort) may interact with Coumadin, increasing the probability of serious unwanted effects like bleeding or blood clots.

This will not be a whole list of all interactions which could occur. Ask your doctor if Coumadin may talk with other medicines that you take. Check with your doctor prior to starting, stop, or alter the dose from a medicine.

Important safety information:

• Tell your doctor or dentist that you just take Coumadin before you have any medical or dentistry, emergency care, or surgery.
• Do NOT take greater than the recommended dose or use for more than prescribed without checking with your physician. Contact your doctor without delay if you might have taken an excessive amount of Coumadin.
• Do not drink alcohol while you take Coumadin; it may well improve the risk of Coumadin's unwanted effects.
• Do not change you activity level or weight without checking with your doctor; the risk of Coumadin's unwanted side effects could possibly be increased.
• Do not make positive changes to eating habits without checking with a medical expert. Eat a normal, balanced diet. Foods that have high degrees of vitamin K (eg, green vegetables, broccoli, liver, certain vegetable oils) may customize the effect of Coumadin. Ask your medical professional for a listing of foods that will affect Coumadin. Tell your physician if any foods on the list are a portion of your diet plan.
• Do not eat cranberry products or drink cranberry juice as you consider Coumadin. Tell your physician if these items are actually a part of your diet plan.
• Elevated body temperature may raise the effect of Coumadin. Be careful to avoid becoming overheated, especially during hot weather.
• Coumadin decreases blood clotting. Use caution while doing activities like brushing your teeth, flossing, or shaving. Avoid activities that may cause bruising or injury. Seek immediate medical help if you fall or injure yourself. Tell your physician in case you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.
• Do not take aspirin as you take Coumadin unless a medical expert notifys you to. If you already take aspirin for any heart and other condition, talk with a medical expert about whether or not you should continue to go with Coumadin.
• Tell your doctor in case you will be traveling or in the event you is going to be restricted to a bed or chair for a long amount of time (eg, car or airplane ride). This may raise your likelihood of having a blood clot.
• If therapy with Coumadin is stopped, the blood thinning effects takes 2 to 5 days as soon as you stop taking it. Discuss any questions or concerns with a medical expert. Do not suddenly stop taking Coumadin without checking with your medical professional.
• Lab tests, including certain blood clotting tests (eg, PT, INR), could be performed when you use Coumadin. These tests could possibly be utilized to monitor your trouble or check for side effects. Be sure to keep all doctor and lab appointments.
• Use Coumadin with caution in Asian patients; they may be more sensitive to its effects, especially bleeding.
• Use Coumadin with caution in the elderly; they might be more sensitive to its effects, especially bleeding.
• Coumadin needs to be combined with warning in kids; safety and effectiveness in children weren't confirmed. Children may need more frequent diagnostic tests if they use Coumadin.
• If you can be pregnant, you should use an effective way of birth control while you take Coumadin. If you've got questions regarding effective birth control method, talk with your doctor.
• Pregnancy and breast-feeding: Do not use Coumadin if you're pregnant. It has been shown to cause harm to the fetus. Avoid pregnancy when you are taking it. If you think you could be pregnant, get hold of your doctor right away. It is not known if Coumadin is situated in breast milk. If you are or will be breast-feeding when you use Coumadin, check with your physician. Discuss any possible risks to your baby.