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Precautions

 Do NOT use Colchicine if:

• you're allergic to the ingredient in Colchicine

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• the patient is often a child with gout

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• you have liver or kidney problems and you're also taking certain other medicines (eg, atazanavir, clarithromycin, indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, ritonavir or any medicine made up of ritonavir, saquinavir, telithromycin)

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Contact your doctor or health care provider right away if some of these apply to you.

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Some health conditions may interact with Colchicine . Tell your physician or pharmacist for those who have any health conditions, particularly if any of the following sign up for you:

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• if you are pregnant, planning to become pregnant, or are breast-feeding

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• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

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• when you have allergies to medicines, foods, and other substances

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• in case you have a blood disorder, stomach or irregularity, cardiovascular disease, or liver or kidney problems, or if you might be having dialysis

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Some medicines may connect to Colchicine . Tell your health care provider if you are taking every other medicines, especially any with the following:

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• Digoxin, fibrates (eg, fenofibric acid), gemfibrozil, or HMG-Co A reductase inhibitors (eg, simvastatin) for the reason that likelihood of severe or fatal muscle problems could possibly be increased

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• Aprepitant, atazanavir, clarithromycin, cyclosporine, diltiazem, erythromycin, fluconazole, HIV protease inhibitors (eg, fosamprenavir), indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, ranolazine, ritonavir or any medicine made up of ritonavir, saquinavir, telithromycin, or verapamil simply because they could raise the risk of Colchicine 's side effects, including severe or fatal unwanted effects

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• Sympathomimetics (eg, pseudoephedrine, albuterol) because the likelihood of their unwanted effects might be increased

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This is probably not a complete listing of all interactions that may occur. Ask your doctor if Colchicine may talk with other medicines that you simply take. Check with your health care provider before you start, stop, or change the dose from a medicine.

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Important safety information

• Do NOT take more than the recommended dose without checking with your physician.

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• Check with your physician when you use medicines that could potentially cause drowsiness (eg, sleep aids, muscle relaxers) if you are using Colchicine ; it might grow their effects. Ask your pharmacist in case you have questions regarding which medicines might cause drowsiness.

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• Colchicine may lower the ability of your body to fight infection. Avoid experience of individuals who have colds or infections. Tell a medical expert if you notice signs of infection like fever, sore throat, rash, or chills.

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• Colchicine may slow up the number of clot-forming cells (platelets) in your blood. Avoid activities that could cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your physician for those who have dark, tarry, or bloody stools.

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• Accidental ingestion or overdose of Colchicine has been fatal in children and adults. Keep Colchicine out of the reach of children. In case of an overdose, call your doctor or poison control center immediately.

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• If nausea, vomiting, or diarrhea occurs, ask your doctor for approaches to lessen these effects. Contact your doctor right away should you experience severe or persistent diarrhea, nausea, or vomiting.

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• Tell your doctor or dentist which you take Colchicine when you get any medical or dental hygiene, emergency care, or surgery.

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• Rarely, Colchicine may decrease fertility in males. Discuss any questions or concerns with your physician.

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• Colchicine may hinder certain lab tests, including urine tests for red blood cells or hemoglobin. Be sure your doctor and lab personnel know you're taking Colchicine .

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• Lab tests, including complete blood cell counts, kidney function, and liver function, might be performed when you use Colchicine . These tests may be used to monitor your problem or search for side effects. Be sure to keep all doctor and lab appointments.

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• Use Colchicine with caution inside elderly; they might be more responsive to its effects, including muscle and nerve problems.

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• Colchicine ought to be used in combination with extreme caution in youngsters younger 4 years; safety and effectiveness in these children weren't confirmed.

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• Pregnancy and breast-feeding: If you conceive, contact your physician. You will need to discuss the benefits and perils of using Colchicine while you're pregnant. Colchicine can be found in breast milk. If you might be or will likely be breast-feeding when you use Colchicine , consult your medical professional. Discuss any possible risks in your baby.

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