Clomipramine is used to take care of obsessive compulsive disorder (OCD). It helps decrease persistent/unwanted thoughts (obsessions), and it assists in easing the urge to perform duplicated tasks (compulsions such as hand-washing, counting, checking) that interfere with everyday living.

This medication belongs to a class of medications called antidepressants that are tricyclic. It works by restoring the balance of certain substances that are naturalserotonin, amongst others) in the mind.

DIFFERENT USES: This area contains uses of the drug that are not placed in the approved professional labeling for the drug but that could be prescribed by your health care professional. Use this medication for a condition that is detailed in this part only if it has been so prescribed by your health care professional.

This medication has additionally been used to treat depression, panic assaults, and pain that is ongoing.

How to use Anafranil

Read the Medication Guide available from your own pharmacist. Consult your pharmacist or doctor if you have any concerns.

Take this medication by mouth with or without meals as directed by your physician. To lessen negative effects such as stomach upset, clomipramine may be started at a dose that is low given in several doses during the day with meals, and slowly increased as your body gets used to it. For you, the total dose can be taken once daily, usually at bedtime to prevent daytime drowsiness or as directed by your doctor after you have reached the best dose. Frequently, the daily dose will not be more than 250 milligrams for adults and 200 milligrams for young ones and teenagers.

Follow your doctor's instructions carefully. Do not take just about medication or frequently take it more than prescribed. Your condition will not improve any faster and your threat of side impacts such as for instance seizures may be increased. Dosage is based on your condition that is medical and to therapy.

Avoid eating drinking or grapefruit grapefruit juice while being treated with this medication unless your doctor instructs you otherwise. Grapefruit can increase the amount of certain medications in your bloodstream. Consult your pharmacist or doctor for more information.

Utilize this medication regularly in order to have the benefit that is most from it. Continue to take it even if you feel well. To help you remember, use it at the same time(s) each day.

Never suddenly stop using this medication without consulting your medical professional. Some conditions may be even worse when the drug is suddenly stopped. You may experience sweating, dizziness, sickness, vomiting, headache, or irritability if you instantly stop taking this drug. Your dose may gradually need to be decreased.

It might simply take 2 to 3 months or longer ahead of the complete ramifications of this medication are noticed. Inform your doctor if your condition persists or if it worsens.

Side Effects

See section that is also warning.

Dizziness, drowsiness, dry lips, constipation, stomach upset, nausea, vomiting, changes in appetite/weight, flushing, sweating, tiredness and blurred vision may occur. Anxiety signs may temporarily aggravate when you first start clomipramine that is taking. If any of these effects persist or worsen, notify your pharmacist or doctor immediately.

To alleviate dry mouth, suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water or utilize a saliva replacement.

To prevent constipation, maintain a diet adequate in fiber, drink plenty of water, and workout. If you then become constipated while making use of this drug, check with your pharmacist for assist in selecting a laxative (e.g., stimulant-type with stool softener).

Understand that your physician has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have side that is serious.

Tell your physician right away if some of these unlikely but serious side effects happen: mental/mood changes (e.g., confusion, despair, memory problems), enlarged/painful breasts, unwanted breast milk manufacturing, irregular/painful menstrual durations, muscle mass stiffness, ringing into the ears, sexual problems (e.g., decreased sexual ability, changes in desire), shakiness (tremors), numbness/tingling associated with the hands/feet, difficulty urinating.

Tell your doctor right away if any of these rare but extremely serious side effects occur: easy bruising/bleeding, signs of infection (e.g., fever, persistent sore throat), unusual/uncontrolled movements (especially associated with the tongue/face/lips), severe stomach/abdominal pain, dark urine, yellowing of eyes/skin.

This medication may increase serotonin and seldom cause an extremely serious condition called serotonin syndrome/toxicity. The risk increases you take if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs. Get medical help right away in the event that you develop a number of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscles, unexplained fever, unusual agitation/restlessness.

Get medical help right away in the event that you have very serious side effects, including: black stools, upper body pain, fainting, slow/fast/irregular heartbeat, seizures, vomit that looks like coffee grounds, eye pain/swelling/redness, vision modifications (such as seeing rainbows around lights through the night).

A very severe reaction that is allergic this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of this face/tongue/throat), severe dizziness, trouble breathing.

This isn't a complete list of possible adverse effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the usa -

Call your physician for medical advice about side effects. You may report effects that are side FDA at 1-800-FDA-1088 or at

In Canada - Call your doctor for medical advice about adverse effects. You might report side effects to Health Canada at 1-866-234-2345.


Before taking clomipramine, tell your doctor or pharmacist if you are allergic to it; or to other tricyclic antidepressants (e.g., imipramine, nortriptyline); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Speak to your pharmacist for more details.

Before by using this medication, tell your doctor or pharmacist your medical history, especially of: blood problems (age.g., purpura, thrombocytopenia), breathing problems (age.g., asthma, chronic bronchitis), individual or genealogy and family history of glaucoma (angle-closure type), eating disorders (age.g., bulimia), heart problems (e.g., arrhythmias, coronary artery disease, recent heart attack), intestinal problems (e.g., chronic constipation, ileus), liver problems, kidney problems, personal or genealogy of other mental/mood conditions (e.g., manic depression, schizophrenia), history of hospitalization for a very serious a reaction to certain medicines (neuroleptic cancerous syndrome), heartburn/stomach acid into the esophagus (e.g., due to hiatal hernia), seizures, overactive thyroid (hyperthyroidism), trouble urinating (urinary retention, enlarged prostate), any condition that may raise your risk of seizures (e.g., alcohol/sedative dependency, utilization of electroconvulsive therapy, mind injury/disease), particular types of tumors (e.g., pheochromocytoma, neuroblastoma).

Clomipramine may cause an ailment that affects the heart rhythm (QT prolongation). QT prolongation can seldom cause severe (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that want medical attention right away.

The threat of QT prolongation are increased if you have actually certain conditions that are medical are using other drugs that could cause QT prolongation. Before using clomipramine, inform your medical professional or pharmacist of the many drugs you are taking and in case you've got any one of the next conditions: certain heart disease (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).

Lower levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your physician about making use of clomipramine safely.

This drug could make you dizzy or drowsy or cause temporary blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision you can perform such activities safely until you are sure. Limit alcoholic beverages.

To decrease dizziness and lightheadedness, get up slowly when increasing from a seated or position that is lying.

Before having surgery, tell your doctor or dentist that you are taking this medication.

Caution is recommended when utilizing this drug in kids who participate in active recreations since it might increase the possibility of heart problems. (See also the Warning section.)

Older adults may be more delicate to your relative unwanted effects with this drug, especially bleeding, confusion, dizziness, and QT prolongation (see above).

This medication should be used only when clearly needed during pregnancy. Newborns exposed to clomipramine during pregnancy may experience withdrawal symptoms or side-effects. Inform your doctor right away if you notice jitteriness, shaking, feeding problems, fast breathing, or seizures in your newborn.

Since untreated mental/mood problems (such as for instance obsessive compulsive disorder, depression, panic attack) can be a serious condition, do not stop taking this medication unless directed by your doctor. You may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy if you are planning pregnancy, become pregnant, or think.

This drug passes into breast milk that can have undesirable effects on a nursing baby. Check with your doctor before breast-feeding.

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