This medication is used to treat severe acne that is cysticalso known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing facial oil (sebum) production. High amounts of sebum can lead to acne that is severe. If left untreated, severe acne may cause scarring that is permanent.

OTHER USES: This area contains uses of this drug which are not detailed in the approved professional labeling for the drug but which could be prescribed by your health care expert. Make use of this drug for a condition that is listed in this section as long as it has been so prescribed by your wellness care professional.

This medication are often used to treat a certain type of cancer (neuroblastoma).

Utilizing Accutane

Read the Medication Guide given by your pharmacist before you start using isotretinoin and each time you get a refill. Read and sign a Patient Information/Informed Consent form before you start taking this medication. If you have any relevant questions about isotretinoin, consult with your doctor or pharmacist before taking the medication.

Swallow capsules whole. Don't crush or chew them. Isotretinoin is usually taken twice daily for 15-20 weeks, or as directed by your doctor. Directions for many generic forms of isotretinoin state that it must certanly be taken with meals. Nevertheless, the FDA has indicated that the Absorica brand may be taken with or without food. Food helps increase absorption of this drug into your bloodstream. Ask your pharmacist or doctor for lots more information. Take this drug with a glass that is full of, and do not lie down for 10 moments after taking it.

The dosage is dependant on your condition that is medical, and reaction to treatment.

Your acne may worsen throughout the first couple of days of using this medication, plus it may take up to 1-2 months before you notice the benefit that is full of medication. A second course of treatment may be started after you have stopped taking the drug for 2 months if severe acne returns. The manufacturer does not suggest use that is long-term of. Do not take more than the recommended dose.

Since this drug could be consumed through the skin and lung area and may harm an unborn baby, women who are pregnant or who could become pregnant should not handle this medication or inhale the dust from the capsules.

adverse Effects

Dry lips and mouth, minor swelling of the eyelids or lips, crusty epidermis, nosebleeds, upset stomach, or thinning of locks may happen. If some of these effects persist or worsen, tell your pharmacist or doctor promptly.

To relieve dry mouth, suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water, or use a saliva substitute.

Keep in mind that the medical practitioner has recommended this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have adverse that is serious.

Tell your doctor right away in the event that you have actually any of these unlikely but adverse that is serious: mental/mood changes (e.g., depression, aggressive or violent behavior, plus in unusual cases, thoughts of suicide), tingling feeling in your skin, quick/severe sunburn (sun sensitivity), back/joint/muscle discomfort, signs of illness (e.g., fever, persistent sore throat), painful swallowing, peeling epidermis on palms/soles.

Isotretinoin may hardly ever cause disease of the pancreas (pancreatitis) that may seldom be fatal. Stop taking this medication and inform your physician right away in the event that you develop: serious stomach pain, severe or nausea/vomiting that is persistent.

Stop using this medication and tell your doctor appropriate away if you develop these unlikely but very serious side effects: serious headache, vision changes, tinnitus, hearing loss, chest pain, yellowing eyes/skin, dark urine, severe diarrhoea, rectal blood.

A very severe reaction that is allergic this drug is rare. However, seek immediate attention that is medical you notice any symptoms of a serious allergic effect, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, difficulty breathing.

This isn't a complete list of possible side effects. If you notice other effects not listed above, contact your pharmacist or doctor.

Within the US -

Phone your physician for medical advice about unwanted effects. You could report side effects to FDA at 1-800-FDA-1088 or at

In Canada - Phone your doctor for medical advice about adverse effects. You might report side effects to Health Canada at 1-866-234-2345.


Before taking isotretinoin, tell your physician or pharmacist if you are allergic to it; or to vitamin A-related drugs (other retinoids such as tretinoin); or if you have any other allergies. This product may contain ingredients that are inactivesuch as soybean, parabens), which can cause allergic reactions or other dilemmas. Some those who are allergic to peanuts may be allergic to also soy. Speak to your pharmacist for more information.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, family or personal history of high blood fats (triglycerides), family or personal history of psychiatric disorders (including depression), liver disease, obesity, eating disorders (e.g., anorexia nervosa), alcohol abuse, pancreatitis, bone loss conditions (e.g., osteoporosis/osteomalacia, decreased bone density).

Do not donate blood after you stop taking it while you are taking isotretinoin and for at least 1 month.

This medicine may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when out-of-doors.

Isotretinoin can affect your vision night. Do not drive, use machinery, or do any activity that requires clear vision after dark you can perform such activities safely until you are sure.

If you wear contact lenses, you may not tolerate them as well as usual while using this medication. Contact your medical practitioner to get more information.

Do not have procedures that are cosmetic smooth your skin (e.g., waxing, laser, dermabrasion) during and for 6 months after isotretinoin therapy. Skin scarring might occur.

Avoid the application of alcohol while taking this medication because it might increase the possibility of certain negative effects (e.g., pancreatitis).

Restricted information indicates isotretinoin may cause some bone loss effects. Therefore, playing contact or repetitive impact sports (e.g., football, basketball, soccer, tennis) may result in bone problems, including an increased risk of broken bones. Limited information also suggests isotretinoin may stop normal growth in some children (epiphyseal dish closing). Check with your physician for more details.

Caution is advised when making use of this medication into the elderly because they might be more painful and sensitive to its impacts, especially the effects on bones.

Care is recommended when using this drug in young ones because they may be more sensitive to its impacts, especially back/joint/muscle pain.

This medication must not be utilized during pregnancy or by people who may become expecting during treatment. You may be pregnant, inform your doctor right away if you become pregnant or think. See also Warning section.

Since this drug may be absorbed through skin and lungs and may harm an baby that is unborn females that are pregnant or who may become pregnant must not handle this medicine or breathe the dust from the capsules.

You must have two pregnancy that is negative before starting this medication. You must have a pregnancy that is monthly during treatment with isotretinoin. If the test is good, you must stop taking this medication and check with your physician right away.

It's unknown if this medication passes into breast milk. However, similar medications pass into breast milk. Breast-feeding while making use of this drug is not recommended. Consult your medical practitioner before breast-feeding.

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